Intravesical cationic nanoparticles of chitosan and polycaprolactone for the delivery of Mitomycin C to bladder tumors

Erem Bilensoy, Can Sarısözen, Güneş Esendağlı, +4

International Journal of Pharmaceutics

Cell-based Drug DeliveryNanomedicineIntravesical Cationic NanoparticlesMitomycin CPolymer-drug Conjugate +4

The effect of co-delivery of paclitaxel and curcumin by transferrin-targeted PEG-PE-based mixed micelles on resistant ovarian cancer in 3-D spheroids and in vivo tumors

Can Sarısözen, Abraham H. Abouzeid, Vladimir P. Torchilin

European Journal of Pharmaceutics and Biopharmaceutics

NanomedicineResistant Ovarian CancerDrug TargetingEngineering3-D Spheroids +9

Anti-cancer activity of doxorubicin-loaded liposomes co-modified with transferrin and folic acid

Shravan Kumar Sriraman, G. Salzano, Can Sarısözen, +1

European Journal of Pharmaceutics and Biopharmaceutics

NanomedicineMedicinal ChemistryNanotherapeuticsDoxorubicin-loaded LiposomesMedicine +7

Indoleamine 2,3-dioxygenase (IDO): Only an enzyme or a checkpoint controller?

Cemil Bilir, Can Sarısözen

Journal of Oncological Sciences

Reductive StressIdo FunctionsAldehyde DehydrogenaseCheckpoint ControllerBiochemistry +13

Nanomedicine based curcumin and doxorubicin combination treatment of glioblastoma with scFv-targeted micelles: In vitro evaluation on 2D and 3D tumor models

Can Sarısözen, Shekhar Dhokai, Edcar G. Tsikudo, +3

European Journal of Pharmaceutics and Biopharmaceutics

NanoparticlesNanomedicineNeuro-oncologyEngineeringPolymer-drug Conjugate +10

Polyamidoamine dendrimers-based nanomedicine for combination therapy with siRNA and chemotherapeutics to overcome multidrug resistance

Jiayi Pan, Lívia P. Mendes, Momei Yao, +5

European Journal of Pharmaceutics and Biopharmaceutics

NanomedicineNanotherapeuticsEngineeringPolymer-drug ConjugateMedicine +10

Mixed Nanosized Polymeric Micelles as Promoter of Doxorubicin and miRNA‐34a Co‐Delivery Triggered by Dual Stimuli in Tumor Tissue

Giuseppina Salzano, Daniel F. Costa, Can Sarısözen, +4

Small

EngineeringBiomedical EngineeringTumor BiologyNanomedicineTherapeutic Nanomaterials +16

PEG-PE-based micelles co-loaded with paclitaxel and cyclosporine A or loaded with paclitaxel and targeted by anticancer antibody overcome drug resistance in cancer cells

Can Sarısözen, İmran Vural, Tatyana Levchenko, +1

Drug Delivery

Transferrin-Targeted Polymeric Micelles Co-loaded with Curcumin and Paclitaxel: Efficient Killing of Paclitaxel-Resistant Cancer Cells

Abraham H. Abouzeid, Niravkumar R. Patel, Can Sarısözen, +1

Pharmaceutical Research

NanomedicineDrug TargetingEfficient KillingMedicinePolymer-drug Conjugate +8

Enhanced Cytotoxicity of Folic Acid-Targeted Liposomes Co-Loaded with C6 Ceramide and Doxorubicin: <i>In Vitro</i> Evaluation on HeLa, A2780-ADR, and H69-AR Cells

Shravan Kumar Sriraman, Jiayi Pan, Can Sarısözen, +2

Molecular Pharmaceutics

C6 CeramideImmunologyCell DeathPharmacotherapyMedicinal Chemistry +16