The BCR-ABL inhibitor ponatinib inhibits platelet immunoreceptor tyrosine-based activation motif (ITAM) signaling, platelet activation and aggregate formation under shear

Cassandra P. Loren, Joseph E. Aslan, Rachel A. Rigg, +5

Thrombosis Research

ThrombopoiesisThrombosisAggregate FormationBlood PlateletMedicine +9

Oral administration of Bruton's tyrosine kinase inhibitors impairs GPVI-mediated platelet function

Rachel A. Rigg, Joseph E. Aslan, Laura D. Healy, +7

American Journal of Physiology-Cell Physiology

Tyrosine KinaseImmunologyBlood CellPlatelet PathobiologyOral Administration +23

Neutralizing blood-borne polyphosphate in vivo provides safe thromboprotection

Linda Labberton, Ellinor Kenne, Andy T. Long, +8

Nature Communications

A physical sciences network characterization of circulating tumor cell aggregate transport

Michael R. King, Kevin G. Phillips, Annachiara Mitrugno, +13

American Journal of Physiology-Cell Physiology

EngineeringBiological MicroenvironmentsCell BiophysicsBiomedical EngineeringCellular Physiology +19

Protease-activated receptor 4 activity promotes platelet granule release and platelet-leukocyte interactions

Rachel A. Rigg, Laura D. Healy, Tiffany T. Chu, +13

Platelets

ImmunologySerine ProteasesGranule ReleaseInflammationThrombosis +17

Quantification of cellular volume and sub-cellular density fluctuations: comparison of normal peripheral blood cells and circulating tumor cells identified in a breast cancer patient

Kevin G. Phillips, Anand Kolatkar, Kathleen Rees, +6

Frontiers in Oncology

Factor XII Activation Promotes Platelet Consumption in the Presence of Bacterial-Type Long-Chain Polyphosphate In Vitro and In Vivo

Jevgenia Zilberman‐Rudenko, Stéphanie E. Reitsma, Cristina Puy, +14

Arteriosclerosis Thrombosis and Vascular Biology

The thrombotic potential of circulating tumor microemboli: computational modeling of circulating tumor cell-induced coagulation

Kevin G. Phillips, Angela M. Lee, Garth W. Tormoen, +8

American Journal of Physiology-Cell Physiology

EngineeringBlood CellBiomedical EngineeringBlood FlowThrombosis +20

Approaching expert results using a hierarchical cerebellum parcellation protocol for multiple inexpert human raters

John Bogovic, Bruno Jedynak, Rachel A. Rigg, +4

NeuroImage

Expert ResultsCognitive ScienceNeuropsychologyMedicineNeurolinguistics +11

Heat shock protein 70 regulates platelet integrin activation, granule secretion and aggregation

Rachel A. Rigg, Laura D. Healy, Marie S. Nowak, +5

American Journal of Physiology-Cell Physiology

ImmunologyGranule SecretionPlatelet AggregationHematologyChaperones +20