Splenectomy reduces infarct volume and neuroinflammation in male but not female mice in experimental stroke

Abby L. Dotson, Jianming Wang, Julie A. Saugstad, +2

Journal of Neuroimmunology

Cerebrovascular DiseaseFemale MiceCerebral Vascular RegulationNeurovascular DiseaseThrombosis +15

Sex differences and the role of PPAR alpha in experimental stroke

Abby L. Dotson, Jianming Wang, Yingxin Chen, +4

Metabolic Brain Disease

ThrombosisCardiovascular DiseaseMedicineStroke-related ConditionSex Differences +11

Omalizumab may decrease IgE synthesis by targeting membrane IgE+ human B cells

Marcia A. Chan, Nicole M. Gigliotti, Abby L. Dotson, +1

Clinical and Translational Allergy

PD-L1 Monoclonal Antibody Treats Ischemic Stroke by Controlling Central Nervous System Inflammation

Sheetal Bodhankar, Yingxin Chen, Andrew Lapato, +5

Stroke

Deferiprone, an orally deliverable iron chelator, ameliorates experimental autoimmune encephalomyelitis

Katherine Mitchell, Abby L. Dotson, Kelli M. Cool, +3

Multiple Sclerosis Journal

Variations in Rodent Models of Type 1 Diabetes: Islet Morphology

Lesya Novikova, Irina V. Smirnova, Sonia Rawal, +3

Journal of Diabetes Research

ImmunologyImmune RegulationInsulin SignalingInflammationType 1 +17

Recombinant T-cell receptor ligand RTL1000 limits inflammation and decreases infarct size after experimental ischemic stroke in middle-aged mice

Wenbin Zhu, Abby L. Dotson, Nicole Libal, +4

Neuroscience

ImmunologyCerebrovascular DiseaseNeuroinflammationInflammationThrombosis +15

Partial MHC Constructs Treat Thromboembolic Ischemic Stroke Characterized by Early Immune Expansion

Abby L. Dotson, Yingxin Chen, Wenbin Zhu, +3

Translational Stroke Research

ThrombosisImmunological MemoryAutoimmune DiseaseIschemic StrokeStroke +13

Different immunological mechanisms govern protection from experimental stroke in young and older mice with recombinant TCR ligand therapy

Abby L. Dotson, Wenbin Zhu, Nicole Libal, +2

Frontiers in Cellular Neuroscience

Immune RegulationImmunologyCerebrovascular DiseaseImmunotherapyUnited States +22

Adoptive transfer of immune subsets prior to MCAO does not exacerbate stroke outcome in splenectomized mice

Jianming Wang, Abby L. Dotson, Stephanie J. Murphy, +2

Journal of Systems and Integrative Neuroscience

ImmunologyImmune RegulationPathologySpleen CellsImmunotherapy +22