METTL3 facilitates tumor progression via an m6A-IGF2BP2-dependent mechanism in colorectal carcinoma

Ting Li, Pei-Shan Hu, Zhixiang Zuo, +14

Molecular Cancer

Targeting BMI1 + Cancer Stem Cells Overcomes Chemoresistance and Inhibits Metastases in Squamous Cell Carcinoma

Demeng Chen, Man-Si Wu, Li Yang, +11

Cell stem cell

Tumor BiologyInhibits MetastasesOncologySquamous Cell CarcinomaMedicine +11

Dermal β-catenin activity in response to epidermal Wnt ligands is required for fibroblast proliferation and hair follicle initiation

Demeng Chen, Andrew Jarrell, Canting Guo, +2

Development

Hair Follicle InitiationDermatologyTissue DevelopmentWnt LigandsCell Signaling +14

Aberrant translation regulated by METTL1/WDR4‐mediated tRNA N7‐methylguanosine modification drives head and neck squamous cell carcinoma progression

Jie Chen, Kang Li, Jianwen Chen, +12

Cancer Communications

Dynamic m6A mRNA methylation reveals the role of METTL3-m6A-CDCP1 signaling axis in chemical carcinogenesis

Fan Yang, Huan Jin, Biao Que, +13

Oncogene

METTL3 Promotes Tumorigenesis and Metastasis through BMI1 m6A Methylation in Oral Squamous Cell Carcinoma

Lin Liu, Yu Wu, Qiuli Li, +12

Molecular Therapy

Super enhancer inhibitors suppress MYC driven transcriptional amplification and tumor progression in osteosarcoma

Demeng Chen, Zhiqiang Zhao, Zixin Huang, +13

Bone Research

Single-Cell Analysis Reveals a Hair Follicle Dermal Niche Molecular Differentiation Trajectory that Begins Prior to Morphogenesis

K. Gupta, Jonathan Levinsohn, George C. Linderman, +8

Developmental Cell

Skin DevelopmentLineage PlasticityDevelopmental BiologyMedicineSingle-cell Genomics +8

Heterogeneous microenvironmental stiffness regulates pro-metastatic functions of breast cancer cells

Miao Li, Zhaoxia Dong, Dong Jiang, +6

Acta Biomaterialia

MechanobiologyBreast OncologyEngineeringBreast Cancer CellsBiological Microenvironments +11

Long non-coding RNA HoxA-AS3 interacts with EZH2 to regulate lineage commitment of mesenchymal stem cells

Xinxing Zhu, Yawei Yan, Demeng Chen, +7

Oncotarget

Regenerative MedicineMesenchymal Stem CellsLineage PlasticitySclerostinDevelopmental Biology +12