Pamela L. Heard

Antioxidants can inhibit basal autophagy and enhance neurodegeneration in models of polyglutamine disease

Benjamin R. Underwood, Sara Imarisio, Angeleen Fleming et al. · Human Molecular Genetics · 2010 · 157 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Development of a toxicogenomics signature for genotoxicity using a dose‐optimization and informatics strategy in human cells

Heng‐Hong Li, Daniel R. Hyduke, Renxiang Chen et al. · Environmental and Molecular Mutagenesis · 2015 · 101 citations · Full text

Pharmacy, Toxicology, Mechanisms Of Toxicity +16

Surface Zn-proteinase as a molecule for defense of Leishmania mexicana amazonensis promastigotes against cytolysis inside macrophage phagolysosomes

M B Seay, Pamela L. Heard, Gautam Chaudhuri · Infection and Immunity · 1996 · 68 citations · Full text

Veterinary Medicine, Immunology, Infectious Diseases +17

Potential impurities in drug substances: Compound-specific toxicology limits for 20 synthetic reagents and by-products, and a class-specific toxicology limit for alkyl bromides

Joel P. Bercu, Sheila M. Galloway, Patricia Parris et al. · Regulatory Toxicology and Pharmacology · 2018 · 47 citations

Pharmacy, Pharmaceutical Analysis, Toxicology +14

Histone markers identify the mode of action for compounds positive in the TK6 micronucleus assay

Jennifer Cheung, Donna Dickinson, Jocelyn Moss et al. · Mutation Research/Genetic Toxicology and Environmental Mutagenesis · 2014 · 21 citations

Life Sciences, Biochemistry, Molecular Biology +13