Lin Liu

Rescue of conformational dynamics in enzyme catalysis by directed evolution

Renee Otten, Lin Liu, Michael W. Clarkson et al. · Nature Communications · 2018 · 139 citations · Full text

Conformational Dynamics, Increased Catalysis, Biochemistry +14

Ensemble-based enzyme design can recapitulate the effects of laboratory directed evolution in silico

Aron Broom, Rojo V. Rakotoharisoa, Michael C. Thompson et al. · Nature Communications · 2020 · 122 citations · Full text

Expanding the space of protein geometries by computational design of de novo fold families

Xingjie Pan, Michael C. Thompson, Lin Liu et al. · Science · 2020 · 80 citations · Full text

Protein Assembly, Biomolecular Structure Prediction, Structural Bioinformatics +19

HIV-1 Vif-mediated ubiquitination/degradation of APOBEC3G involves four critical lysine residues in its C-terminal domain

Yasumasa Iwatani, Denise Chan, Lin Liu et al. · Proceedings of the National Academy of Sciences · 2009 · 66 citations · Full text

Viral Replication, Protein Assembly, Immunology +22

Domain Swapping Proceeds via Complete Unfolding: A ¹⁹F- and ¹H-NMR Study of the Cyanovirin-N Protein

Lin Liu, In‐Ja L. Byeon, İvet Bahar et al. · Journal of the American Chemical Society · 2012 · 60 citations · Full text

Protein Assembly, Molecular Biology, Overall Unfolding +16