Haochen Yang

Exhaustion-associated cholesterol deficiency dampens the cytotoxic arm of antitumor immunity

Chengsong Yan, Lin Zheng, Shutan Jiang et al. · Cancer Cell · 2023 · 205 citations · Full text

Life Sciences, Cancer Biology, Immunology +16

Ligand-induced ubiquitination unleashes LAG3 immune checkpoint function by hindering membrane sequestration of signaling motifs

Yong Jiang, Anran Dai, Yuwei Huang et al. · Cell · 2025 · 60 citations · Full text

Life Sciences, Immunology, Molecular Biology +12

Phase separation of chimeric antigen receptor promotes immunological synapse maturation and persistent cytotoxicity

Xinyi Xu, Haotian Chen, Xiaomin Xu et al. · Immunity · 2024 · 31 citations

Life Sciences, Immunology, Molecular Biology +15

Cellular basis of enhanced humoral immunity to SARS-CoV-2 upon homologous or heterologous booster vaccination analyzed by single-cell immune profiling

Jingwen Ai, Jingxin Guo, H. C. Zhang et al. · Cell Discovery · 2022 · 24 citations · Full text

Veterinary Medicine, Immunology, Infectious Diseases +17

Shaping immune landscape of colorectal cancer by cholesterol metabolites

Yibing Bai, Tongzhou Li, Qinshu Wang et al. · EMBO Molecular Medicine · 2024 · 23 citations · Full text

Medicine, Immunology, Oncology +17