Pascal Syren

TREK-1 (K2P2.1) K+ channels are suppressed in patients with atrial fibrillation and heart failure and provide therapeutic targets for rhythm control

Patrick Lugenbiel, Fabian Wenz, Pascal Syren et al. · Basic Research in Cardiology · 2016 · 47 citations

Cardiac Muscle, Channelopathies, Heart Failure +10

Inhibition of Histone Deacetylases Induces K+ Channel Remodeling and Action Potential Prolongation in HL-1 Atrial Cardiomyocytes

Patrick Lugenbiel, Katharina Govorov, Ann‐Kathrin Rahm et al. · Cellular Physiology and Biochemistry · 2018 · 20 citations · Full text

Epigenetic regulation of cardiac electrophysiology in atrial fibrillation: HDAC2 determines action potential duration and suppresses NRSF in cardiomyocytes

Patrick Lugenbiel, Katharina Govorov, Pascal Syren et al. · Basic Research in Cardiology · 2021 · 16 citations

Cardiac Muscle, Cardiomyopathy, Heart Failure +14

Atrial myofibroblast activation and connective tissue formation in a porcine model of atrial fibrillation and reduced left ventricular function

Patrick Lugenbiel, Fabian Wenz, Katharina Govorov et al. · Life Sciences · 2017 · 15 citations

Mechanobiology, Porcine Model, Connective Tissue Formation +13

Histone deacetylase 2-dependent ventricular electrical remodeling in a porcine model of early heart failure

Pascal Syren, Ann‐Kathrin Rahm, Patrick A. Schweizer et al. · Life Sciences · 2021 · 11 citations

Porcine Model, Cardiac Muscle, Cardiomyopathy +10