Effects of mixed polyethyleneglycol modification on fixed aqueous layer thickness and antitumor activity of doxorubicin containing liposome

Yasuyuki Sadzuka, Akiko Nakade, Rieko Hirama, +4

International Journal of Pharmaceutics

NanomedicineMedicinal ChemistryAntitumor ActivityEngineeringPolymer-drug Conjugate +6

Determination of the Thickness of the Fixed Aqueous Layer Around Polyethyleneglycol-coated Liposomes

Kazuhiko Shimada, Atsuo Miyagishima, Yasuyuki Sadzuka, +4

Journal of drug targeting

Sodium ChlorideNanomedicineLipid PreparationMembrane FormationEngineering +11

Freeze-dried nifedipine-lipid nanoparticles with long-term nano-dispersion stability after reconstitution

Hiroyuki Ohshima, Atsuo Miyagishima, Takurou Kurita, +4

International Journal of Pharmaceutics

NanoparticlesEngineeringNanomaterialsFreeze-dried Nifedipine-lipid NanoparticlesProtein Nanoparticles

The effects of theanine, as a novel biochemical modulator, on the antitumor activity of adriamycin

Yasuyuki Sadzuka, Tomomi Sugiyama, Atsuo Miyagishima, +2

Cancer Letters

Medicinal ChemistryPharmaceutical ScienceAntitumor ActivityBiochemistryMedicine +7

Determination of incorporated amounts of poly(ethylene glycol)-derivatized lipids in liposomes for the physicochemical characterization of stealth liposomes

Kazuhiko Shimada, Sanshiro Matsuo, Yasuyuki Sadzuka, +4

International Journal of Pharmaceutics

Lipid AnalysisLipid PreparationEthylene GlycolEngineeringBiochemistry +7

Preparation and dissolution characteristics of griseofulvin solid dispersions with saccharides

Masataka Saito, Takashi Ugajin, Yasuo Nozawa, +3

International Journal of Pharmaceutics

Materials ScienceDissolution CharacteristicsMicroemulsionFood EngineeringChemistry +1

Application of principal component analysis enables to effectively find important physical variables for optimization of fluid bed granulator conditions

Tomoko Otsuka, Yasunori Iwao, Atsuo Miyagishima, +1

International Journal of Pharmaceutics

EngineeringImportant Physical VariablesMechanical EngineeringGranular MediumMultiphase Flow +4

The Effect of Dose on the Distribution of Adriamycin Encapsulated in Polyethyleneglycol-Coated Liposomes

Yasuyuki Sadzuka, Shin-ichiro Nakai, Atsuo Miyagishima, +2

Journal of drug targeting

NanomedicinePharmacological StudyPolymer-drug ConjugateMedicineImmunology +11

Effects of administered route on tissue distribution and antitumor activity of polyethyleneglycol-coated liposomes containing adriamycin

Yasuyuki Sadzuka, Shin-ichiro Nakai, Atsuo Miyagishima, +2

Cancer Letters

Cell-based Drug DeliveryNanomedicineAntitumor ActivityPolymer-drug ConjugateTissue Distribution +5

Stabilization Mechanism of Clarithromycin Tablets under Gastric pH Conditions

Sadahiro Fujiki, Yasunori Iwao, Mika Kobayashi, +2

Chemical and Pharmaceutical Bulletin

Pharmaceutical ScienceEngineeringGastroenterologyPharmacotherapyDrug Resistance +14