Concepedia

Author

Tyrell R. Towle

University of Iowa

Also Known As

Tyrell R. Towle, Tyrell Robert Towle, Tyrell Towle

9

Publications

168

Citations

7

H-Index

23

Concepts

All Affiliations

University of IowaUniversity of Minnesota Medical CenterRutgers, The State University of New Jersey
TR

About

Tyrell R. Towle is an author at University of Iowa specializing in chemical biology, natural sciences, and drug discovery.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Natural Sciences

5

5

147

2

Biochemistry

4

4

103

3

Medicine

3

3

75

4

Engineering

1

1

62

5

Biomolecular Engineering

1

1

62

Tyrell R. Towle

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5

Publications

147

Citations

5

H-Index

YearCitations

Hidden Histidine Radical Rearrangements upon Electron Transfer to Gas-Phase Peptide Ions. Experimental Evidence and Theoretical Analysis

František Tureček, Jace W. Jones, Tyrell R. Towle,

Journal of the American Chemical Society

2008

62

Bypassing Fluoroquinolone Resistance with Quinazolinediones: Studies of Drug–Gyrase–DNA Complexes Having Implications for Drug Design

Karl Drlica, Arkady Mustaev, Tyrell R. Towle,

ACS Chemical Biology

2014

44

Design, synthesis, and evaluation of novel N-1 fluoroquinolone derivatives: Probing for binding contact with the active site tyrosine of gyrase

Tyrell R. Towle, Chaitanya A. Kulkarni, Lisa M. Oppegard,

Bioorganic & Medicinal Chemistry Letters

2018

21

Chemical probes of a trisubstituted pyrrole to identify its protein target(s) in Plasmodium sporozoites

Tyrell R. Towle, Isabel Chang, Robert J. Kerns,

Bioorganic & Medicinal Chemistry Letters

2013

10

Fluoroquinolones stimulate the DNA cleavage activity of topoisomerase IV by promoting the binding of Mg2+ to the second metal binding site

Lisa M. Oppegard, Heidi A. Schwanz, Tyrell R. Towle,

Biochimica et Biophysica Acta (BBA) - General Subjects

2015

10

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