Pericytes regulate vascular immune homeostasis in the CNS

Orsolya Török, Bettina Schreiner, Johanna Schaffenrath, +15

Proceedings of the National Academy of Sciences

IFNγ and GM-CSF control complementary differentiation programs in the monocyte-to-phagocyte transition during neuroinflammation

Ana Amorim, Donatella De Feo, Ekaterina Friebel, +9

Nature Immunology

InflammationSignal TransductionCell SignalingMedicineImmunology +9

IL-17 controls central nervous system autoimmunity through the intestinal microbiome

Tommy Regen, Sandrine Isaac, Ana Amorim, +23

Science Immunology

Graft-versus-host disease, but not graft-versus-leukemia immunity, is mediated by GM-CSF–licensed myeloid cells

Sònia Tugues, Ana Amorim, Sabine Spath, +14

Science Translational Medicine

Cell TherapyGm-csf NeutralizationImmunologyImmune RegulationCell Replacement Therapy +24

Inactivation of sphingosine-1-phosphate receptor 2 (S1PR2) decreases demyelination and enhances remyelination in animal models of multiple sclerosis

Maryam Seyedsadr, Oliver Weinmann, Ana Amorim, +6

Neurobiology of Disease

Neurological DisorderMedicineImmunologyEnhances RemyelinationSphingosine-1-phosphate Receptor 2 +9

MicroRNA-146a controls functional plasticity in γδ T cells by targeting NOD1

Nina Schmolka, Pedro H. Papotto, Paula Vargas Romero, +11

Science Immunology

Single-cell profiling of immune system alterations in lymphoid, barrier and solid tissues in aged mice

Sinduya Krishnarajah, Florian Ingelfinger, Ekaterina Friebel, +19

Nature Aging

InflammationAutoimmune DiseaseLymphocyte DevelopmentAdaptive Immune SystemImmunology +9

MicroRNA-181a regulates IFN-γ expression in effector CD8+ T cell differentiation

Tiago Amado, Ana Amorim, Francisco J. Enguita, +9

Journal of Molecular Medicine

Protection against autoimmunity is driven by thymic epithelial cell–mediated regulation of T _reg development

Claudia Haftmann, Pascale Zwicky, Florian Ingelfinger, +12

Science Immunology