Alexandria M. Doerfler

AAV-CRISPR Gene Editing Is Negated by Pre-existing Immunity to Cas9

Ang Li, Mark R. Tanner, Ciaran M. Lee et al. · Molecular Therapy · 2020 · 217 citations · Full text

A Self-Deleting AAV-CRISPR System for In Vivo Genome Editing

Ang Li, Ciaran M. Lee, Ayrea Hurley et al. · Molecular Therapy — Methods & Clinical Development · 2018 · 122 citations · Full text

Somatic Editing of <i>Ldlr</i> With Adeno-Associated Viral-CRISPR Is an Efficient Tool for Atherosclerosis Research

Kelsey E. Jarrett, Ciaran M. Lee, Marco De Giorgi et al. · Arteriosclerosis Thrombosis and Vascular Biology · 2018 · 76 citations · Full text

LPA disruption with AAV-CRISPR potently lowers plasma apo(a) in transgenic mouse model: A proof-of-concept study

Alexandria M. Doerfler, So Hyun Park, Julia M. Assini et al. · Molecular Therapy — Methods & Clinical Development · 2022 · 32 citations · Full text

Lpa Disruption, Knockout Mouse, Transgenic Mouse Models +13

Targeting the Apoa1 locus for liver-directed gene therapy

Marco De Giorgi, Ang Li, Ayrea Hurley et al. · Molecular Therapy — Methods & Clinical Development · 2021 · 25 citations · Full text