HPV integration hijacks and multimerizes a cellular enhancer to generate a viral-cellular super-enhancer that drives high viral oncogene expression

Alix Warburton, Catherine J. Redmond, Katharine Dooley, +6

PLoS Genetics

Viral ReplicationGeneticsHpv Integration HijacksImmunologyHpv16 Integration +15

Tandemly Integrated HPV16 Can Form a Brd4-Dependent Super-Enhancer-Like Element That Drives Transcription of Viral Oncogenes

Katharine Dooley, Alix Warburton, Alison A. McBride

mBio

The Epstein-Barr Virus Episome Maneuvers between Nuclear Chromatin Compartments during Reactivation

Stephanie Moquin, Sean Thomas, Sean Whalen, +5

Journal of Virology

Recurrent integration of human papillomavirus genomes at transcriptional regulatory hubs

Alix Warburton, Tovah E. Markowitz, Joshua P. Katz, +2

npj Genomic Medicine

Characterization of a REST-Regulated Internal Promoter in the Schizophrenia Genome-Wide Associated Gene MIR137

Alix Warburton, Gerome Breen, Dan Rujescu, +2

Schizophrenia Bulletin

Transcriptional RegulationDistinct IsoformsPsychiatryMedicineGenetics +13

A GWAS SNP for Schizophrenia Is Linked to the Internal MIR137 Promoter and Supports Differential Allele-Specific Expression

Alix Warburton, Gerome Breen, Vivien J. Bubb, +1

Schizophrenia Bulletin

Schizophrenia IsGeneticsEpigeneticsPsychiatric GeneticsPsychiatry +14

Sp100 colocalizes with HPV replication foci and restricts the productive stage of the infectious cycle

Wesley H. Stepp, James D. Stamos, Simran Khurana, +2

PLoS Pathogens

Hpv Replication FociViral ReplicationImmunologyMolecular BiologySp100 Bound +15

NRSF and BDNF polymorphisms as biomarkers of cognitive dysfunction in adults with newly diagnosed epilepsy

Alix Warburton, Fábio Miyajima, Kanvel Shazadi, +6

Epilepsy & Behavior

Novel brain expressed RNA identified at the MIR137 schizophrenia-associated locus

Olympia Gianfrancesco, Alix Warburton, David Collier, +2

Schizophrenia Research

Molecular signatures of mood stabilisers highlight the role of the transcription factor REST/NRSF

Alix Warburton, Abigail L. Savage, Paul Myers, +3

Journal of Affective Disorders