Apoptotic Vesicles Crossprime CD8 T Cells and Protect against Tuberculosis

Florian Winau, Stephan Weber, Subash Sad, +7

Immunity

ImmunologyAntigen ProcessingAutoimmunityT Cell ImmunityCd4 T Cell Responses +3

The epidermal barrier function is dependent on the serine protease CAP1/<i>Prss8 </i>

Céline Leyvraz, Roch‐Philippe Charles, Isabelle Rubera, +5

The Journal of Cell Biology

PAR2 absence completely rescues inflammation and ichthyosis caused by altered CAP1/Prss8 expression in mouse skin

Simona Frateschi, Eric Camerer, Giovanna Crisante, +14

Nature Communications

Altered Cap1/prss8 ExpressionImmunologyImmune RegulationSkin DisordersDermatology +22

Human Acid Ceramidase

Klaus Ferlinz, Guido Kopal, Katussevani Bernardo, +7

Journal of Biological Chemistry

Role for LAMP-2 in endosomal cholesterol transport

Alexander Schneede, Christine K. Schmidt, Maarit Hölttä‐Vuori, +11

Journal of Cellular and Molecular Medicine

OxysterolBiochemistryNatural SciencesAutophagyEndocytic Pathway +12

Normal epidermal differentiation but impaired skin-barrier formation upon keratinocyte-restricted IKK1 ablation

Ralph Gareus, Marion Huth, Bernadette Breiden, +6

Nature Cell Biology

Impaired Skin-barrier FormationSkin DevelopmentDevelopmental BiologyKeratinocyte-restricted Ikk1 AblationNormal Epidermal Differentiation +10

Schlank, a member of the ceramide synthase family controls growth and body fat in Drosophila

Reinhard Bauer, André Voelzmann, Bernadette Breiden, +6

The EMBO Journal

BiologyDevelopmental BiologySignal TransductionCeramide Synthase FamilyDevelopmental Genetics +6

Sphingolipid Storage Affects Autophagic Metabolism of the Amyloid Precursor Protein and Promotes Aβ Generation

Irfan Y. Tamboli, Heike Hampel, Nguyen T. Tien, +6

Journal of Neuroscience

Promotes Aβ GenerationNeurochemical BiomarkersExtracellular Amyloid PlaquesAmyloid Precursor ProteinCell Autophagy +14

Role of endosomal membrane lipids and NPC2 in cholesterol transfer and membrane fusion

Misbaudeen Abdul-Hammed, Bernadette Breiden, Matthew A. Adebayo, +3

Journal of Lipid Research

Membrane FusionProteinlipid InteractionBiochemistryEndosomal Membrane LipidsAtherosclerosis +13

Acid sphingomyelinase activity is regulated by membrane lipids and facilitates cholesterol transfer by NPC2

Vincent O. Oninla, Bernadette Breiden, Jonathan O. Babalola, +1

Journal of Lipid Research