Ya-Wen Fu

Efficient precise knockin with a double cut HDR donor after CRISPR/Cas9-mediated double-stranded DNA cleavage

Jianping Zhang, Xiaolan Li, Guohua Li et al. · Genome biology · 2017 · 481 citations · Full text

Dynamics and competition of CRISPR–Cas9 ribonucleoproteins and AAV donor-mediated NHEJ, MMEJ and HDR editing

Ya-Wen Fu, Xinyue Dai, Wentian Wang et al. · Nucleic Acids Research · 2020 · 181 citations · Full text

Systems Biology, Off-target Effect, Crispr Gene Knockout +15

Highly efficient genome editing via CRISPR–Cas9 in human pluripotent stem cells is achieved by transient BCL-XL overexpression

Xiaolan Li, Guohua Li, Juan Fu et al. · Nucleic Acids Research · 2018 · 117 citations · Full text

Engineering, In Vivo Gene Therapy, Genetics +23

Effective control of large deletions after double-strand breaks by homology-directed repair and dsODN insertion

Wei Wen, Zi-Jun Quan, Si-Ang Li et al. · Genome biology · 2021 · 81 citations · Full text

Curing hemophilia A by NHEJ-mediated ectopic F8 insertion in the mouse

Jianping Zhang, Xinxin Cheng, Mei Zhao et al. · Genome biology · 2019 · 75 citations · Full text