Heat Shock Protein gp96 Is a Master Chaperone for Toll-like Receptors and Is Important in the Innate Function of Macrophages

Yi Yang, Bei Liu, Jie Dai, +4

Immunity

InflammationToll-like ReceptorsCytokineSignal TransductionInnate Immune System +10

IL-10 Elicits IFNγ-Dependent Tumor Immune Surveillance

John B. Mumm, Jan Emmerich, Xueqing Zhang, +28

Cancer Cell

Immune EvasionCancer ImmunosurveillanceImmunologyTumor ImmunityImmunologic Mechanism +3

Cell surface expression of an endoplasmic reticulum resident heat shock protein gp96 triggers MyD88-dependent systemic autoimmune diseases

Bei Liu, Jie Dai, Hong Zheng, +3

Proceedings of the National Academy of Sciences

Cell Surface Targeting of Heat Shock Protein gp96 Induces Dendritic Cell Maturation and Antitumor Immunity

Hong Zheng, Jie Dai, Diliana Stoilova, +1

The Journal of Immunology

TLR4 Up-Regulation at Protein or Gene Level Is Pathogenic for Lupus-Like Autoimmune Disease

Bei Liu, Yi Yang, Jie Dai, +4

The Journal of Immunology

Microbial PathogensInnate Immune SystemImmunologyInnate ImmunityTlr4 Up-regulation +23

4-1BB and OX40 Dual Costimulation Synergistically Stimulate Primary Specific CD8 T Cells for Robust Effector Function

Seungjoo Lee, Lara Myers, Guruprasaadh Muralimohan, +5

The Journal of Immunology

Cell surface expression of heat shock protein gp96 enhances cross-presentation of cellular antigens and the generation of tumor-specific T cell memory.

Jie Dai, Bei Liu, M.M. Caudill, +4

PubMed

Heat Shock ProteinCell Surface ExpressionCancer ImmunosurveillanceCell Surface Gp96Immunology +13

Optimal Lymph Node Examination and Adjuvant Chemotherapy for Stage I Lung Cancer

Jie Dai, Ming Liu, Yang Yang, +17

Journal of Thoracic Oncology

Medical ImagingCancer DetectionMedicineMultiple Pulmonary NoduleAdjuvant Chemotherapy +6

Preclinical Development of the Anti-LAG-3 Antibody REGN3767: Characterization and Activity in Combination with the Anti-PD-1 Antibody Cemiplimab in Human <i>PD-1xLAG-3</i> –Knockin Mice

Elena Burova, Aynur Hermann, Jie Dai, +17

Molecular Cancer Therapeutics

Regulatory T cells and Toll-like receptors: What is the missing link?

Jie Dai, Bei Liu, Zihai Li

International Immunopharmacology

InflammationToll-like ReceptorsAutoimmune DiseaseAdaptive Immune SystemT-regulatory Cell +9