Patrick A. Howson

(S)-3,4-DCPG, a potent and selective mGlu8a receptor agonist, activates metabotropic glutamate receptors on primary afferent terminals in the neonatal rat spinal cord

Nicola Thomas, Rebecca A. Wright, Patrick A. Howson et al. · Neuropharmacology · 2001 · 147 citations

Life Sciences, Neuroscience, Pharmacology +16

PYM50028, a novel, orally active, nonpeptide neurotrophic factor inducer, prevents and reverses neuronal damage induced by MPP ⁺ in mesencephalic neurons and by MPTP in a mouse model of Parkinson's disease

Naomi P. Visanji, Antonia Orsi, Tom H. Johnston et al. · The FASEB Journal · 2008 · 76 citations

Life Sciences, Neuroscience, Pharmacology +17

Beneficial Effects of Trehalose on Striatal Dopaminergic Deficits in Rodent and Primate Models of Synucleinopathy in Parkinson’s Disease

Patrick A. Howson, Paula Ravenscroft, Michael P. Hill et al. · Journal of Pharmacology and Experimental Therapeutics · 2019 · 29 citations · Full text

Medicine, Neuroscience, Pharmacology +17

Smilagenin attenuates beta amyloid (25–35)-induced degeneration of neuronal cells via stimulating the gene expression of brain-derived neurotrophic factor

R. Zhang, Z. Wang, Patrick A. Howson et al. · Neuroscience · 2012 · 28 citations

Life Sciences, Neurobiology, Neuroscience +17

Pharmacokinetic/Pharmacodynamic Correlation Analysis of Amantadine for Levodopa-Induced Dyskinesia

Elizabeth Brigham, Tom H. Johnston, Carl D. Brown et al. · Journal of Pharmacology and Experimental Therapeutics · 2018 · 25 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +16