John R. Hoidal

Proteinase 3. A distinct human polymorphonuclear leukocyte proteinase that produces emphysema in hamsters.

R C Kao, Nancy Wehner, Keith M. Skubitz et al. · Journal of Clinical Investigation · 1988 · 431 citations · Full text

Asthma, Inflammatory Lung Disease, Lung Inflammation +13

Transforming growth factor-β1 induces Nox4 NAD(P)H oxidase and reactive oxygen species-dependent proliferation in human pulmonary artery smooth muscle cells

Anne Sturrock, Barbara C. Cahill, Kimberly G. Norman et al. · American Journal of Physiology-Lung Cellular and Molecular Physiology · 2005 · 395 citations

Lung Inflammation, Pulmonary Hypertension, Hpasmc Proliferation +16

Potential mechanism of emphysema: alpha 1-proteinase inhibitor recovered from lungs of cigarette smokers contains oxidized methionine and has decreased elastase inhibitory capacity.

H. Carp, Frederick W. Miller, John R. Hoidal et al. · Proceedings of the National Academy of Sciences · 1982 · 344 citations · Full text

Asthma, Methionine Sulfoxide, Methionine Oxidation +17

Acute exercise stress activates Nrf2/ARE signaling and promotes antioxidant mechanisms in the myocardium

Vasanthi R. Muthusamy, Sankaranarayanan Kannan, Kamal Sadhaasivam et al. · Free Radical Biology and Medicine · 2011 · 304 citations

Reductive Stress, Kinesiology, Exercise +8

Characterization of proteinase-3 (PR-3), a neutrophil serine proteinase. Structural and functional properties

N. V. Rao, Nancy Wehner, Bruce C. Marshall et al. · Journal of Biological Chemistry · 1991 · 300 citations · Full text

Protein Secretion, Functional Properties, Protein Assembly +18