Oncogenic transcription factor Evi1 regulates hematopoietic stem cell proliferation through GATA‐2 expression

Hiromi Yuasa, Yuichi Oike, Atsushi Iwama, +6

The EMBO Journal

A novel EVI1 gene family, MEL1, lacking a PR domain (MEL1S) is expressed mainly in t(1;3)(p36;q21)-positive AML and blocks G-CSF–induced myeloid differentiation

Ichiro Nishikata, Hidenori Sasaki, Mutsunori Iga, +5

Blood

Aberrant expression of the MEL1S gene identified in association with hypomethylation in adult T-cell leukemia cells

Mika Yoshida, Kisato Nosaka, Jun‐ichirou Yasunaga, +3

Blood

Analysis of hepatitis C virus (HCV) RNA in the lesions of lichen planus in patients with chronic hepatitis C: detection of anti-genomic- as well as genomic-strand HCV RNAs in lichen planus lesions

Motoki Kurokawa, Tomonori Hidaka, Hidenori Sasaki, +3

Journal of Dermatological Science

Diagnostic VirologyHepatologyHepatitis CViral HepatitisHepatitis +6

Measurement of human immunodeficiency virus type 1 p24 in serum by an ultrasensitive enzyme immunoassay, the two-site immune complex transfer enzyme immunoassay

Seiichi Hashida, Kazuya Hashinaka, Ichiro Nishikata, +6

Journal of Clinical Microbiology

Primary ImmunodeficiencyDiagnostic VirologyMedicineHuman RetrovirusImmunology +12

Immune complex transfer enzyme immunoassay that is more sensitive and specific than western blotting for detection of antibody immunoglobulin G to human immunodeficiency virus type 1 in serum with recombinant pol and gag proteins as antigens

Seiichi Hashida, Kazuya Hashinaka, Ichiro Nishikata, +7

Clinical and Diagnostic Laboratory Immunology

Recombinant PolAntibody Immunoglobulin GImmunologyImmunotherapyImmunoassays +15

Shortening of the window period in diagnosis of HIV-1 infection by simultaneous detection of p24 antigen and antibody IgG to p17 and reverse transcriptase in serum with ultrasensitive enzyme immunoassay

Seiichi Hashida, Kazuya Hashinaka, Ichiro Nishikata, +6

Journal of Virological Methods

Primary ImmunodeficiencyAutoimmune DiseaseViral DiagnosticsMedicineHuman Retrovirus +9

Acetylation of Lysine 564 Adjacent to the C-terminal Binding Protein-binding Motif in EVI1 Is Crucial for Transcriptional Activation of GATA2

Akiko Shimahara, Norio Yamakawa, Ichiro Nishikata, +1

Journal of Biological Chemistry

Molecular RegulationMolecular BiologyImportant Transcription FactorEpigeneticsEvi1-binding Site +15

Ultrasensitive and more specific enzyme immunoassay (immune complex transfer enzyme immunoassay) for p24 antigen of HIV-1 in serum using affinity-purified rabbit anti-p24 Fab′ and monoclonal mouse anti-p24 Fab′

Seiichi Hashida, Kazuya Hashinaka, Ichiro Nishikata, +4

Journal of Clinical Laboratory Analysis

Sumoylation of MEL1S at lysine 568 and its interaction with CtBP facilitates its repressor activity and the blockade of G-CSF-induced myeloid differentiation

Ichiro Nishikata, Shingo Nakahata, Yusuke Saito, +3

Oncogene

Protein FunctionSignal TransductionLysine 568Signaling PathwayNatural Sciences +8