Multiple Organ System Defects and Transcriptional Dysregulation in the Nipbl+/− Mouse, a Model of Cornelia de Lange Syndrome

Shimako Kawauchi, Anne L. Calof, Rosaysela Santos, +12

PLoS Genetics

AMPK-HDAC5 pathway facilitates nuclear accumulation of HIF-1α and functional activation of HIF-1 by deacetylating Hsp70 in the cytosol

Shuyang Chen, Chengqian Yin, Taotao Lao, +4

Cell Cycle

Molecular RegulationMolecular BiologyRedox BiologyFunctional ActivationOxidative Stress +17

A Chronic Obstructive Pulmonary Disease Susceptibility Gene, <i>FAM13A</i> , Regulates Protein Stability of β-Catenin

Zhiqiang Jiang, Taotao Lao, Weiliang Qiu, +17

American Journal of Respiratory and Critical Care Medicine

Functional interactors of three genome-wide association study genes are differentially expressed in severe chronic obstructive pulmonary disease lung tissue

Jarrett D. Morrow, Xiaobo Zhou, Taotao Lao, +16

Scientific Reports

Nitrogen anabolism underlies the importance of glutaminolysis in proliferating cells

Meng Meng, Shuyang Chen, Taotao Lao, +2

Cell Cycle

Cell ProliferationMetabolic RemodelingWarburg EffectRedox BiologyOxidative Stress +14

Haploinsufficiency of Hedgehog interacting protein causes increased emphysema induced by cigarette smoke through network rewiring

Taotao Lao, Kimberly Glass, Weiliang Qiu, +12

Genome Medicine

<i>Hhip</i> haploinsufficiency sensitizes mice to age-related emphysema

Taotao Lao, Zhiqiang Jiang, Jeong H. Yun, +12

Proceedings of the National Academy of Sciences

Exome Array Analysis Identifies a Common Variant in <i>IL27</i> Associated with Chronic Obstructive Pulmonary Disease

Brian D. Hobbs, Margaret M. Parker, Han Chen, +32

American Journal of Respiratory and Critical Care Medicine

Gene expression analysis uncovers novel hedgehog interacting protein (HHIP) effects in human bronchial epithelial cells

Xiaobo Zhou, Weiliang Qiu, J. Fah Sathirapongsasuti, +18

Genomics

AsthmaKnockout MouseSignaling PathwayInflammatory Lung DiseaseHedgehog Interacting Protein +7

CG14906 (mettl4) mediates m6A methylation of U2 snRNA in Drosophila

Lei Gu, Longfei Wang, Hao Chen, +15

Cell Discovery

Epigenetic ChangeGeneticsMolecular BiologyU2 SnrnaMolecular Genetics +14