Acute hypoxia induces apoptosis of pancreatic β-cell by activation of the unfolded protein response and upregulation of CHOP

Xiaowei Zheng, Xiaowei Zheng, X Wang, +10

Cell Death and Disease

Hepatoprotective effect of methyl ferulic acid against carbon tetrachloride-induced acute liver injury in rats

Cheng‐Fang Yang, Li Li, Zuheng Ma, +5

Experimental and Therapeutic Medicine

Facilitation of fatty acid uptake by CD36 in insulin-producing cells reduces fatty-acid-induced insulin secretion and glucose regulation of fatty acid oxidation

Tina Wallin, Zuheng Ma, Hirotaka Ogata, +5

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

ObesityMetabolic SyndromeInsulin SignalingBiochemistryDiabetes +11

Hyperoxia inhibits glucose-induced insulin secretion and mitochondrial metabolism in rat pancreatic islets

Zuheng Ma, Noah Moruzzi, Sergiu‐Bogdan Catrina, +2

Biochemical and Biophysical Research Communications

Metabolic SyndromeBiochemistryDiabetesPhysiologyMetabolic Regulation +9

Diabetes reduces β-cell mitochondria and induces distinct morphological abnormalities, which are reproducible by high glucose in vitro with attendant dysfunction

Zuheng Ma, Tina Wirström, Lisa Borg, +5

Islets

Effects of Diazoxide on Gene Expression in Rat Pancreatic Islets Are Largely Linked to Elevated Glucose and Potentially Serve to Enhance β-Cell Sensitivity

Zuheng Ma, Neil Portwood, David Brodin, +2

Diabetes

Insulin SignalingOxidative StressMetabolic SyndromeElevated GlucoseHealth Sciences +14

Short-term intermittent exposure to diazoxide improves functional performance of β-cells in a high-glucose environment

Hiroyasu YOSHIKAWA, Zuheng Ma, Anneli Björklund, +1

American Journal of Physiology-Endocrinology and Metabolism

High-glucose EnvironmentRedox BiologyInsulin SignalingContinuous DiazoxideOxidative Stress +17

NOX4/ROS mediate ethanol‑induced apoptosis via MAPK signal pathway in L‑02 cells

Cheng‐Fang Yang, Yujuan Zhong, Zuheng Ma, +7

International Journal of Molecular Medicine

L‑02 Liver CellsApoptosisCell DeathPathologyL‑02 Cells +21

Preconditioning with Associated Blocking of Ca2+ Inflow Alleviates Hypoxia-Induced Damage to Pancreatic β-Cells

Zuheng Ma, Noah Moruzzi, Sergiu‐Bogdan Catrina, +4

PLoS ONE

Investigating optimal β‐cell‐preserving treatment in latent autoimmune diabetes in adults: Results from a 21‐month randomized trial

Ingrid K. Hals, Hanne Fiskvik Fleiner, Nina Reimers, +5

Diabetes Obesity and Metabolism