Kelly E. Fisher

GSK1120212 (JTP-74057) Is an Inhibitor of MEK Activity and Activation with Favorable Pharmacokinetic Properties for Sustained <i>In Vivo</i> Pathway Inhibition

Aidan G. Gilmartin, Maureen R. Bleam, Arthur Groy et al. · Clinical Cancer Research · 2011 · 601 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +13

Discovery and Characterization of a Cell-Permeable, Small-Molecule c-Abl Kinase Activator that Binds to the Myristoyl Binding Site

Jingsong Yang, Nino Campobasso, Mangatt P. Biju et al. · Chemistry & Biology · 2011 · 116 citations

Life Sciences, Cell Biology, Molecular Biology +9

Discovery of GSK1070916, a Potent and Selective Inhibitor of Aurora B/C Kinase

Nicholas D. Adams, Jerry L. Adams, Joelle L. Burgess et al. · Journal of Medicinal Chemistry · 2010 · 111 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Pazopanib Enhances Paclitaxel-Induced Mitotic Catastrophe in Anaplastic Thyroid Cancer

Crescent R. Isham, Ayoko R. Bossou, Vivian Negron et al. · Science Translational Medicine · 2013 · 69 citations · Full text

Medicine, Oncology, Pharmacology +17

Abstract B88: A selective Raf kinase inhibitor induces cell death and tumor regression of human cancer cell lines encoding B-RafV600E mutation

Sylvie Laquerre, Marc R. Arnone, Katherine G. Moss et al. · Molecular Cancer Therapeutics · 2009 · 54 citations

Medicine, Cancer Biology, Oncology +15