Management of Pulmonary Arterial Hypertension During Pregnancy

Alexander G. Duarte, Shibu Thomas, Zeenat Safdar, +4

CHEST Journal

HypertensionPulmonary Arterial HypertensionMaternal Cardiovascular OutcomeGestational HypertensionGynecology +6

Erdafitinib in patients with advanced solid tumours with FGFR alterations (RAGNAR): an international, single-arm, phase 2 study

Shubham Pant, Martin Schüler, Gopa Iyer, +103

The Lancet Oncology

Fgfr AlterationsMedicinePathologyAdvanced Solid TumoursFibroblast Growth Factor +5

CD24 Is an Effector of HIF-1–Driven Primary Tumor Growth and Metastasis

Shibu Thomas, Michael A. Harding, Steven C. Smith, +6

Cancer Research

Tumor BiologyTranscriptional RegulationCd24 PromoterMedicineCd24 Mrna +8

CD24 Offers a Therapeutic Target for Control of Bladder Cancer Metastasis Based on a Requirement for Lung Colonization

Jonathan B. Overdevest, Shibu Thomas, Glen Kristiansen, +3

Cancer Research

Apalutamide plus abiraterone acetate and prednisone versus placebo plus abiraterone and prednisone in metastatic, castration-resistant prostate cancer (ACIS): a randomised, placebo-controlled, double-blind, multinational, phase 3 study

Fred Saad, Eleni Efstathiou, Gerhardt Attard, +17

The Lancet Oncology

UrologyOncologyPrednisone Versus PlaceboAbiraterone AcetateMedicine +5

Androgen receptor mutations in patients with castration-resistant prostate cancer treated with apalutamide

Dana E. Rathkopf, Matthew R. Smith, Charles J. Ryan, +18

Annals of Oncology

UrologyOncologyMedicineAndrogen Receptor MutationsCastration-resistant Prostate Cancer +3

CD24 expression is important in male urothelial tumorigenesis and metastasis in mice and is androgen regulated

Jonathan B. Overdevest, Kristina H. Knubel, Jason E. Duex, +7

Proceedings of the National Academy of Sciences

Src and Caveolin-1 Reciprocally Regulate Metastasis via a Common Downstream Signaling Pathway in Bladder Cancer

Shibu Thomas, Jonathan B. Overdevest, Matthew D. Nitz, +6

Cancer Research

Discovery, design, and synthesis of anti-metastatic lead phenylmethylene hydantoins inspired by marine natural products

Mudit Mudit, Mohammad A. Khanfar, Muralidharan Anbalagan, +4

Bioorganic & Medicinal Chemistry

Combinatorial ChemistryMedicinal ChemistryHeterocyclicNatural SciencesMarine Natural Products +4

Plasma tumor gene conversions after one cycle abiraterone acetate for metastatic castration-resistant prostate cancer: a biomarker analysis of a multicenter international trial

Anuradha Jayaram, Anna Wingate, Daniel Wetterskog, +15

Annals of Oncology

Multicenter International TrialUrologyBiomarker AnalysisGenitourinary CancerMedicine +7