Hematopoietic loss of Y chromosome leads to cardiac fibrosis and heart failure mortality

Soichi Sano, Keita Horitani, Hayato Ogawa, +22

Science

Heart FailureGeneticsGenetic EpidemiologyImmunologyPathology +22

Tet2-mediated clonal hematopoiesis in nonconditioned mice accelerates age-associated cardiac dysfunction

Ying Wang, Soichi Sano, Yoshimitsu Yura, +14

JCI Insight

Heart FailureImmunologyCardiac Progenitor CellsPathologyBlood Cell +19

The Cancer Therapy-Related Clonal Hematopoiesis Driver Gene <i>Ppm1d</i> Promotes Inflammation and Non-Ischemic Heart Failure in Mice

Yoshimitsu Yura, Emiri Miura‐Yura, Yasufumi Katanasaka, +15

Circulation Research

InflammationVisual LanguageHeart FailureNon-ischemic Heart FailureDisease Pathophysiology +10

Glucagon-Like Peptide-1 Receptor Agonist Protects Dorsal Root Ganglion Neurons against Oxidative Insult

Mohammad Sarif Mohiuddin, Tatsuhito Himeno, Rieko Inoue, +15

Journal of Diabetes Research

Disruption of the Uty epigenetic regulator locus in hematopoietic cells phenocopies the profibrotic attributes of Y chromosome loss in heart failure

Keita Horitani, Nicholas W. Chavkin, Yohei Arai, +16

Nature Cardiovascular Research

Secreted Factors from Stem Cells of Human Exfoliated Deciduous Teeth Directly Activate Endothelial Cells to Promote All Processes of Angiogenesis

Makoto Kato, Shin Tsunekawa, Nobuhisa Nakamura, +18

Cells

Matrigel Plug AssayAdult Stem CellBiomedical EngineeringStem Cell BiologyRegenerative Medicine +16

Secreted factors from cultured dental pulp stem cells promoted neurite outgrowth of dorsal root ganglion neurons and ameliorated neural functions in streptozotocin‐induced diabetic mice

Emiri Miura‐Yura, Shin Tsunekawa, Keiko Naruse, +13

Journal of Diabetes Investigation

Experimental TET2 Clonal Hematopoiesis Predisposes to Renal Hypertension Through an Inflammasome-Mediated Mechanism

Ariel H. Polizio, Lucila Marino, Kyung‐Duk Min, +12

Circulation Research

Deficiency of glucagon gene-derived peptides induces peripheral polyneuropathy in mice

Mikio Motegi, Tatsuhito Himeno, Hiromi Nakai‐Shimoda, +19

Biochemical and Biophysical Research Communications

Kir6.2-deficient mice develop somatosensory dysfunction and axonal loss in the peripheral nerves

Hiromi Nakai‐Shimoda, Tatsuhito Himeno, Tetsuji Okawa, +16

iScience