SIRT7-mediated ATM deacetylation is essential for its deactivation and DNA damage repair

Ming Tang, Zhiming Li, Chaohua Zhang, +13

Science Advances

Methylation of SUV39H1 by SET7/9 results in heterochromatin relaxation and genome instability

Donglai Wang, Jingyi Zhou, Xiangyu Liu, +14

Proceedings of the National Academy of Sciences

SIRT6 coordinates with CHD4 to promote chromatin relaxation and DNA repair

Tianyun Hou, Ziyang Cao, Jun Zhang, +13

Nucleic Acids Research

Cytoplasmic SIRT6-mediated ACSL5 deacetylation impedes nonalcoholic fatty liver disease by facilitating hepatic fatty acid oxidation

Tianyun Hou, Yuan Tian, Ziyang Cao, +13

Molecular Cell

InflammationOxysterolHepatologyBiochemistryLiver Physiology +8

Destabilization of linker histone H1.2 is essential for ATM activation and DNA damage repair

Zhiming Li, Yinglu Li, Ming Tang, +13

Cell Research

G9a coordinates with the RPA complex to promote DNA damage repair and cell survival

Qiaoyan Yang, Qian Zhu, Xiaopeng Lu, +14

Proceedings of the National Academy of Sciences

SET7/9 regulates cancer cell proliferation by influencing β‐catenin stability

Changchun Shen, Donglai Wang, Xiangyu Liu, +15

The FASEB Journal

Molecular RegulationCancer BiologyEpigeneticsTumor BiologyOxidative Stress +18

Downregulation of SIRT7 by 5-fluorouracil induces radiosensitivity in human colorectal cancer

Ming Tang, Xiaopeng Lu, Chaohua Zhang, +18

Theranostics

ATM-mediated KDM2A phosphorylation is required for the DNA damage repair

L-L Cao, Yangge Du, Bing Song, +10

Oncogene

Atm-mediated Kdm2a PhosphorylationChromatinGenome InstabilityDna DamageChromatin Remodeling +6

Ubiquitin-specific peptidase 7 (USP7)-mediated deubiquitination of the histone deacetylase SIRT7 regulates gluconeogenesis

Lu Jiang, Jiannan Xiong, Junsi Zhan, +12

Journal of Biological Chemistry