Max T. Huang

Fatty acid–induced NLRP3-ASC inflammasome activation interferes with insulin signaling

Haitao Wen, Denis Gris, Yu L. Lei et al. · Nature Immunology · 2011 · 1.7K citations · Full text

Inflammation, Metabolic Syndrome, Diabetes +7

NLRP3 Plays a Critical Role in the Development of Experimental Autoimmune Encephalomyelitis by Mediating Th1 and Th17 Responses

Denis Gris, Zhengmao Ye, Heather A. Iocca et al. · The Journal of Immunology · 2010 · 416 citations · Full text

T-regulatory Cell, Innate Immune System, Immunology +23

NLRP3 (NALP3, Cryopyrin) Facilitates In Vivo Caspase-1 Activation, Necrosis, and HMGB1 Release via Inflammasome-Dependent and -Independent Pathways

Stephen B. Willingham, Irving C. Allen, Dan T. Bergstralh et al. · The Journal of Immunology · 2009 · 346 citations · Full text

NLRP1-Dependent Pyroptosis Leads to Acute Lung Injury and Morbidity in Mice

Martina Kovářová, Pamela R. Hesker, Leigh A. Jania et al. · The Journal of Immunology · 2012 · 272 citations · Full text

Acute Lung Injury, Inflammatory Lung Disease, Nlrp1-dependent Pyroptosis Leads +24

<i>Neisseria gonorrhoeae</i> Activates the Proteinase Cathepsin B to Mediate the Signaling Activities of the NLRP3 and ASC-Containing Inflammasome

Joseph A. Duncan, Xi Gao, Max T. Huang et al. · The Journal of Immunology · 2009 · 266 citations · Full text

Microbial Pathogens, Innate Immune System, Immunology +22