Tara M. Stauffer

Discovery of Dinaciclib (SCH 727965): A Potent and Selective Inhibitor of Cyclin-Dependent Kinases

Kamil Paruch, Michael P. Dwyer, Carmen Álvarez et al. · ACS Medicinal Chemistry Letters · 2010 · 174 citations · Full text

Drug Target, Pathology, Chemical Biology +21

Discovery of 2-Hydroxy-<i>N</i>,<i>N</i>-dimethyl-3-{2-[[(<i>R</i>)-1-(5- methylfuran-2-yl)propyl]amino]-3,4-dioxocyclobut-1-enylamino}benzamide (SCH 527123):  A Potent, Orally Bioavailable CXCR2/CXCR1 Receptor Antagonist

Michael P. Dwyer, Younong Yu, Jianping Chao et al. · Journal of Medicinal Chemistry · 2006 · 113 citations · Full text

Pharmaceutical Science, Drug Target, Immunology +18

Pyrazolo[1,5-a]pyrimidines as orally available inhibitors of cyclin-dependent kinase 2

Kamil Paruch, Michael P. Dwyer, Carmen Álvarez et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 65 citations · Full text

Cyclin-dependent Kinase 2, Biochemistry, Medicine +5

Synthesis and structure–activity relationships of 3,4-diaminocyclobut-3-ene-1,2-dione CXCR2 antagonists

J. Robert Merritt, Laura L. Rokosz, Kingsley H. Nelson et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 46 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Medicine +4

Design, synthesis, and evaluation of tetrahydroquinoline and pyrrolidine sulfonamide carbamates as γ-secretase inhibitors

Tao Guo, Huizhong Gu, Doug W. Hobbs et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 37 citations · Full text

Medicinal Chemistry, Biochemistry, Natural Sciences +8