Laura L. Rokosz

Stromelysin‐1: Three‐dimensional structure of the inhibited catalytic domain and of the C‐truncated proenzyme

Joseph W. Becker, Alice I. Marcy, Laura L. Rokosz et al. · Protein Science · 1995 · 292 citations · Full text

Discovery of 2-Hydroxy-<i>N</i>,<i>N</i>-dimethyl-3-{2-[[(<i>R</i>)-1-(5- methylfuran-2-yl)propyl]amino]-3,4-dioxocyclobut-1-enylamino}benzamide (SCH 527123):  A Potent, Orally Bioavailable CXCR2/CXCR1 Receptor Antagonist

Michael P. Dwyer, Younong Yu, Jianping Chao et al. · Journal of Medicinal Chemistry · 2006 · 113 citations · Full text

Pharmaceutical Science, Drug Target, Immunology +18

Regulation of calcineurin phosphatase activity and interaction with the FK-506.FK-506 binding protein complex.

Janey N. Parsons, Greg Wiederrecht, Scott P. Salowe et al. · Journal of Biological Chemistry · 1994 · 63 citations · Full text

Human Cytoplasmic 3-Hydroxy-3-methylglutaryl Coenzyme A Synthase: Expression, Purification, and Characterization of Recombinant Wild-Type and Cys129 Mutant Enzymes

Laura L. Rokosz, David A. Boulton, E.A. Butkiewicz et al. · Archives of Biochemistry and Biophysics · 1994 · 56 citations

Biosynthesis, Cellular Enzymology, Biochemistry +10

Discovery of Ruzasvir (MK-8408): A Potent, Pan-Genotype HCV NS5A Inhibitor with Optimized Activity against Common Resistance-Associated Polymorphisms

Ling Tong, Wensheng Yu, Lei Chen et al. · Journal of Medicinal Chemistry · 2016 · 47 citations

Medicinal Chemistry, Antiviral Compound, Molecular Virology +14