Identification of Two Origins of Replication in the Single Chromosome of the Archaeon Sulfolobus solfataricus

Nicholas P. Robinson, I. Dionne, Magnus Lundgren, +3

Cell

BiologySingle ChromosomeUnicellular OrganismArchaeon Sulfolobus SolfataricusPhylogenetics +8

Loss of Apc allows phenotypic manifestation of the transforming properties of an endogenous K- <i>ras</i> oncogene <i>in vivo</i>

Owen J. Sansom, Valérie S. Méniel, Julie A. Wilkins, +8

Proceedings of the National Academy of Sciences

Signal TransductionCell RegulationTumor MicroenvironmentOncogenic AgentGenetics +13

Focal Adhesion Kinase Is Required for Intestinal Regeneration and Tumorigenesis Downstream of Wnt/c-Myc Signaling

G H S Ashton, Jennifer P. Morton, Kevin Myant, +16

Developmental Cell

Intestinal RegenerationWnt/c-myc SignalingSignal TransductionFocal Adhesion KinaseSignaling Pathway +11

Epithelial Pten is dispensable for intestinal homeostasis but suppresses adenoma development and progression after Apc mutation

Victoria Marsh, Douglas J. Winton, Geraint T. Williams, +4

Nature Genetics

Apc MutationEpithelial PtenGastroenterologyColorectal CancerPathology +7

Sir2 and the Acetyltransferase, Pat, Regulate the Archaeal Chromatin Protein, Alba

Victoria Marsh, Sew‐Yeu Peak‐Chew, Stephen D. Bell

Journal of Biological Chemistry

GeneticsMolecular BiologyMolecular GeneticsArchaeaEpigenetics +20

Mutationally Activated PIK3CAH1047R Cooperates with BRAFV600E to Promote Lung Cancer Progression

Christy L. Trejo, Shon Green, Victoria Marsh, +4

Cancer Research

<scp>PTEN</scp> loss and <scp>KRAS</scp> activation cooperate in murine biliary tract malignancies

Victoria Marsh, Emma Jane Davies, Geraint T. Williams, +1

The Journal of Pathology

PathologyCholangiopathiesCancer BiologyTumor BiologySignaling Pathway +15

Influence of Chromatin and Single Strand Binding Proteins on the Activity of an Archaeal MCM

Victoria Marsh, Adam McGeoch, Stephen D. Bell

Journal of Molecular Biology

ChromatinProkaryotic SystemNatural SciencesMolecular BiologyDna Replication +4

A limited role for p53 in modulating the immediate phenotype of Apc loss in the intestine

Karen R. Reed, Valérie S. Méniel, Victoria Marsh, +3

BMC Cancer

Effects of Toxoplasma gondii infection on the function and integrity of human cerebrovascular endothelial cells and the influence of verapamil treatment in vitro

Mohammad Syamsul Reza Harun, Victoria Marsh, Nashwa A. Elsaied, +2

Brain Research

ImmunologyEndothelial DysfunctionPathologyVascular BiologyMedicine +1