Zika Virus Replicons for Drug Discovery

Xuping Xie, Jing Zou, Chao Shan, +5

EBioMedicine

A yellow fever–Zika chimeric virus vaccine candidate protects against Zika infection and congenital malformations in mice

Dieudonné Buh Kum, Niraj Mishra, Robbert Boudewijns, +10

npj Vaccines

A Single-Dose Live-Attenuated Zika Virus Vaccine with Controlled Infection Rounds that Protects against Vertical Transmission

Xuping Xie, Dieudonné Buh Kum, Hongjie Xia, +13

Cell Host & Microbe

VaccinationVaccine DevelopmentImmunologyVirologyVaccine Design +4

A chimeric yellow fever-Zika virus vaccine candidate fully protects against yellow fever virus infection in mice

Dieudonné Buh Kum, Robbert Boudewijns, Ji Ma, +4

Emerging Microbes & Infections

Limited evolution of the yellow fever virus 17d in a mouse infection model

Dieudonné Buh Kum, Niraj Mishra, Bram Vrancken, +5

Emerging Microbes & Infections

Susceptible HostGeneticsViral PathogenesisImmunologyImmunodominance +18

The Discovery and Preclinical Profile of ALG-000184, a Prodrug of the Potent Hepatitis B Virus Capsid Assembly Modulator ALG-001075

Sandrine Vendeville, Franck Amblard, Leda Bassit, +29

Journal of Medicinal Chemistry

Class A capsid assembly modulator RG7907 clears HBV-infected hepatocytes through core-dependent hepatocyte death and proliferation

Dieudonné Buh Kum, Hannah Vanrusselt, Abel Acosta Sanchez, +14

Hepatology

A High-Throughput Yellow Fever Neutralization Assay

Madina Rasulova, Thomas Vercruysse, Jasmine Paulissen, +18

Microbiology Spectrum

Comparing immunogenicity and protective efficacy of the yellow fever 17D vaccine in mice

Ji Ma, Robbert Boudewijns, Lorena Sánchez-Felipe, +6

Emerging Microbes & Infections