Chromatin Regulator CHD1 Remodels the Immunosuppressive Tumor Microenvironment in PTEN-Deficient Prostate Cancer

Di Zhao, Li Cai, Xin Lü, +21

Cancer Discovery

RGMb protects against acute kidney injury by inhibiting tubular cell necroptosis via an MLKL-dependent mechanism

Wenjing Liu, Binbin Chen, Yang Wang, +15

Proceedings of the National Academy of Sciences

Immune checkpoint B7-H3 is a therapeutic vulnerability in prostate cancer harboring PTEN and TP53 deficiencies

Wei Shi, Yin Wang, Yuehui Zhao, +11

Science Translational Medicine

Tubule-Specific Mst1/2 Deficiency Induces CKD via YAP and Non-YAP Mechanisms

Chunhua Xu, Li Wang, Wenling Li, +9

Journal of the American Society of Nephrology

IL-1β inhibits β-Klotho expression and FGF19 signaling in hepatocytes

Yueshui Zhao, Chenling Meng, Yang Wang, +7

American Journal of Physiology-Endocrinology and Metabolism

ImmunologyImmune RegulationPathologyRenal InflammationFgf19 Signaling +15

Lethal (3) malignant brain tumor-like 2 (L3MBTL2) protein protects against kidney injury by inhibiting the DNA damage–p53–apoptosis pathway in renal tubular cells

Huihui Huang, Chunhua Xu, Yang Wang, +11

Kidney International

Tumor BiologyKidney InjuryMedicineApoptosisPathology +8

L3MBTL2 regulates chromatin remodeling during spermatogenesis

Chenling Meng, Jinyue Liao, Danfeng Zhao, +5

Cell Death and Differentiation

SpermatogenesisChromatinDevelopmental BiologyChromatin StructureChromatin Remodeling +9

Hippo kinases MST1 and MST2 control the differentiation of the epididymal initial segment via the MEK-ERK pathway

Chenling Meng, Geng Tian, Chunhua Xu, +10

Cell Death and Differentiation

Lineage PlasticityDevelopmental BiologySignal TransductionMek-erk PathwaySignaling Pathway +5

Kidney tubular transcription co-activator, Yes-associated protein 1 (YAP), controls the expression of collecting duct aquaporins and water homeostasis

Yu Zhang, Huihui Huang, Yonglun Kong, +19

Kidney International

Prostaglandin F2α induces expression of activating transcription factor 3 (ATF3) and activates MAPK signaling in the rat corpus luteum

Nannan Guo, Chenling Meng, Wujiao Bai, +4

Acta Histochemica

InflammationTranscriptional RegulationDevelopmental BiologySignal TransductionMolecular Physiology +10