Interaction of platelet-derived autotaxin with tumor integrin αVβ3 controls metastasis of breast cancer cells to bone

Raphaël Leblanc, Sue-Chin Lee, Marion David, +9

Blood

The LPA1/ZEB1/miR-21-activation pathway regulates metastasis in basal breast cancer

Debashish Sahay, Raphaël Leblanc, Thomas G. P. Grünewald, +4

Oncotarget

Cancer ResearchTranscriptional RegulationLpa-induced MetastasisBasal Breast CancerSignaling Pathway +12

ΔNp63α Silences a miRNA Program to Aberrantly Initiate a Wound-Healing Program That Promotes TGFβ-Induced Metastasis

Lidia Rodriguez Calleja, Camille Jacques, François Lamoureux, +13

Cancer Research

Mirna ProgramMetastatic DisseminationTgfβ EffectorsCancer BiologyTumor Biology +20

Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair

María Pilar Sánchez-Bailón, Soo‐Youn Choi, Elizabeth R. Dufficy, +10

Nature Communications

Autotaxin-β interaction with the cell surface via syndecan-4 impacts on cancer cell proliferation and metastasis

Raphaël Leblanc, Debashish Sahay, A Houssin, +2

Oncotarget

Cell AdhesionImmunologyCancer BiologyTumor BiologyAutotaxin-β Interaction +14

Identification of Heparin-Binding EGF-Like Growth Factor (HB-EGF) as a Biomarker for Lysophosphatidic Acid Receptor Type 1 (LPA1) Activation in Human Breast and Prostate Cancers

Marion David, Debashish Sahay, Florence Mege, +5

PLoS ONE

GPCRs profiling and identification of GPR110 as a potential new target in HER2+ breast cancer

Raksha R. Bhat, Puja Yadav, Debashish Sahay, +14

Breast Cancer Research and Treatment

Tumor BiologyHer2+ Breast CancerBreast OncologyEndocrine-related CancerMedicine +10

Circulating tumor cell investigation in breast cancer patient-derived xenograft models by automated immunofluorescence staining, image acquisition, and single cell retrieval and analysis

Arturo B. Ramirez, Raksha R. Bhat, Debashish Sahay, +14

BMC Cancer

Prenatal polycyclic aromatic hydrocarbons, altered ERα pathway-related methylation and expression, and mammary epithelial cell proliferation in offspring and grandoffspring adult mice

Debashish Sahay, Susan E. Lloyd, Janelle Rivera, +7

Environmental Research

Developmental BiologyEarly Life ExposureErα Pathway-related MethylationMedicineEpigenetic Change +8

PRMT5-regulated splicing of DNA repair genes drives chemoresistance in breast cancer stem cells

Matthew S. Gillespie, Kelly Chiang, Gemma L. Regan-Mochrie, +6

Oncogene