Douglas M. Roberts

An unusual<i>Burkholderia gladioli</i>double chain-initiating nonribosomal peptide synthetase assembles ‘fungal’ icosalide antibiotics

Matthew Jenner, Xinyun Jian, Yousef Dashti et al. · Chemical Science · 2019 · 43 citations · Full text

A dual transacylation mechanism for polyketide synthase chain release in enacyloxin antibiotic biosynthesis

Joleen Masschelein, Paulina K. Sydor, Christian Hobson et al. · Nature Chemistry · 2019 · 40 citations · Full text

Biosynthesis, Dual Transacylation Mechanism, Engineering +9

A Flavin-Dependent Decarboxylase–Dehydrogenase–Monooxygenase Assembles the Warhead of α,β-Epoxyketone Proteasome Inhibitors

Daniel Zabala, Joshua W. Cartwright, Douglas M. Roberts et al. · Journal of the American Chemical Society · 2016 · 36 citations

Substrate selectivity of an isolated enoyl reductase catalytic domain from an iterative highly reducing fungal polyketide synthase reveals key components of programming

Douglas M. Roberts, Christoph Bartel, Alan Scott et al. · Chemical Science · 2016 · 33 citations · Full text

Diene incorporation by a dehydratase domain variant in modular polyketide synthases

Christian Hobson, Matthew Jenner, Xinyun Jian et al. · Nature Chemical Biology · 2022 · 10 citations · Full text