Marcin Jakubiec

N-Benzyl-(2,5-dioxopyrrolidin-1-yl)propanamide (AS-1) with Hybrid Structure as a Candidate for a Broad-Spectrum Antiepileptic Drug

Krzysztof Kamiński, Katarzyna Socała, Mirosław Zagaja et al. · Neurotherapeutics · 2019 · 27 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

Discovery of (<i>R</i>)-<i>N</i>-Benzyl-2-(2,5-dioxopyrrolidin-1-yl)propanamide [<b>(<i>R</i>)-AS-1</b>], a Novel Orally Bioavailable EAAT2 Modulator with Drug-like Properties and Potent Antiseizure Activity <i>In Vivo</i>

Michał Abram, Marcin Jakubiec, Katelyn Reeb et al. · Journal of Medicinal Chemistry · 2022 · 24 citations · Full text

Medicine, Neuroscience, Pharmacology +16

The Search for New Anticonvulsants in a Group of (2,5-Dioxopyrrolidin-1-yl)(phenyl)Acetamides with Hybrid Structure—Synthesis and In Vivo/In Vitro Studies

Michał Abram, Marcin Jakubiec, Anna Rapacz et al. · International Journal of Molecular Sciences · 2020 · 11 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13

Identification of New Compounds with Anticonvulsant and Antinociceptive Properties in a Group of 3-substituted (2,5-dioxo-pyrrolidin-1-yl)(phenyl)-Acetamides

Michał Abram, Marcin Jakubiec, Anna Rapacz et al. · International Journal of Molecular Sciences · 2021 · 10 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13