J. Borgulya

Catechol‐<i>O</i>‐methyltransferase‐Inhibiting Pyrocatechol Derivatives: Synthesis and Structure‐Activity Studies

J. Borgulya, H. Bruderer, Karl Bernauer et al. · Helvetica Chimica Acta · 1989 · 113 citations

Bioorganic Chemistry, Clinical Candidate, Exemplary Syntheses +16

Umlagerung von Allyl‐aryläthern und Allyl‐cyclohexadienonen mittels Bortrichlorid

J. Borgulya, R. Madeja, P. Fahrni et al. · Helvetica Chimica Acta · 1973 · 96 citations

Chemical Engineering, Cross-coupling Reaction, Engineering +7

Ro 40-7592, a novel, very potent, and orally active inhibitor of catechol-O-methyltransferase: a pharmacological study in rats.

G. Zürcher, Keller Hh, R. Kettler et al. · PubMed · 1990 · 89 citations

Molecular Pharmacology, Medicinal Chemistry, Active Inhibitor +11

Tolcapone

Jean‐Luc Moreau, J. Borgulya, F. Jenck · Behavioural Pharmacology · 1994 · 69 citations

Stimulation Threshold, Stress Hormone, Psychiatry +13

Improved Therapy of Parkinsonʼs Disease with Tolcapone, a Central and Peripheral COMT Inhibitor with an S-Adenosyl-L-Methionine-Sparing Effect

M. Da Prada, J. Borgulya, Alessandro Napolitano et al. · Clinical Neuropharmacology · 1994 · 44 citations

S-adenosyl-l-methionine-sparing Effect, Pharmacotherapy, Experimental Pharmacology +16