Douglas J. Francis

Identification of sulfated oligosaccharide-based inhibitors of tumor growth and metastasis using novel in vitro assays for angiogenesis and heparanase activity.

Christopher R. Parish, Craig Freeman, Kathryn J. Brown et al. · PubMed · 1999 · 400 citations

Life Sciences, Oncology, Pharmacology +13

DNAzyme Targeting c- <i>jun</i> Suppresses Skin Cancer Growth

Hong Cai, Fernando S. Santiago, Leonel Prado-Lourenço et al. · Science Translational Medicine · 2012 · 282 citations

Medicine, Molecular Biology, Oncology +10

Safety and tolerability of an intratumorally injected DNAzyme, Dz13, in patients with nodular basal-cell carcinoma: a phase 1 first-in-human trial (DISCOVER)

Eunae Sandra Cho, Fergal J. Moloney, Hong Cai et al. · The Lancet · 2013 · 106 citations · Full text

Medicine, Oncology, Molecular Oncology +7

Blockade of Vascular Smooth Muscle Cell Proliferation and Intimal Thickening After Balloon Injury by the Sulfated Oligosaccharide PI-88

Douglas J. Francis, Christopher R. Parish, Mark McGarry et al. · Circulation Research · 2003 · 58 citations

Medicine, Cardiology, Pharmacology +15