Alexander S. Freed

Evaluation of protein adsorption and preferred binding regions in multimodal chromatography using NMR

Wai Keen Chung, Alexander S. Freed, Melissa Holstein et al. · Proceedings of the National Academy of Sciences · 2010 · 78 citations · Full text

Engineering, Molecular Biology, Labeled Human Ubiquitin +22

Investigation of protein binding affinity in multimodal chromatographic systems using a homologous protein library

Wai Keen Chung, Ying Hou, Melissa Holstein et al. · Journal of Chromatography A · 2009 · 54 citations

Protein Chemistry, Homologous Protein Library, Protein Assembly +11

Molecular Simulations of Multimodal Ligand–Protein Binding: Elucidation of Binding Sites and Correlation with Experiments

Alexander S. Freed, Shekhar Garde, Steven M. Cramer · The Journal of Physical Chemistry B · 2011 · 47 citations

Engineering, Protein Assembly, Molecular Biology +20

Investigation of protein binding affinity and preferred orientations in ion exchange systems using a homologous protein library

Wai Keen Chung, Ying Hou, Alexander S. Freed et al. · Biotechnology and Bioengineering · 2008 · 38 citations · Full text

Homologous Protein Library, Protein Assembly, Molecular Biology +18

Probing multimodal ligand binding regions on ubiquitin using nuclear magnetic resonance, chromatography, and molecular dynamics simulations

Melissa Holstein, Wai Keen Chung, Siddharth Parimal et al. · Journal of Chromatography A · 2012 · 37 citations

Biochemistry, Medicine, Natural Sciences +11