Jesús Troya

Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths

Paul Bastard, Adrian Gervais, Tom Le Voyer et al. · Science Immunology · 2021 · 600 citations · Full text

Characteristics and predictors of death among 4035 consecutively hospitalized patients with COVID-19 in Spain

Juan Berenguer, Pablo Ryan, Jesús Rodríguez‐Baño et al. · Clinical Microbiology and Infection · 2020 · 418 citations · Full text

Long Covid, Global Health, Covid-19 Pandemic +8

X-linked recessive TLR7 deficiency in ~1% of men under 60 years old with life-threatening COVID-19

Takaki Asano, Bertrand Boisson, Fanny Onodi et al. · Science Immunology · 2021 · 410 citations · Full text

Dolutegravir plus lamivudine versus dolutegravir plus tenofovir disoproxil fumarate and emtricitabine in antiretroviral-naive adults with HIV-1 infection (GEMINI-1 and GEMINI-2): week 48 results from two multicentre, double-blind, randomised, non-inferiority, phase 3 trials

Pedro Cahn, Juan Sierra Madero, José Ramón Arribas et al. · The Lancet · 2018 · 371 citations · Full text

Hiv/aids Counselling, Treatment And Prevention, Week 48 +14

The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies

Jérémy Manry, Paul Bastard, Adrian Gervais et al. · Proceedings of the National Academy of Sciences · 2022 · 180 citations · Full text

Ifn Autoantibodies, Immunology, Age Dependent +16