Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

Daniel J. Klionsky, Hagai Abeliovich, Patrizia Agostinis, +78

Autophagy

Shikonin and its analogs inhibit cancer cell glycolysis by targeting tumor pyruvate kinase-M2

J Chen, Jiaxin Xie, Zhinong Jiang, +3

Oncogene

Tumor BiologyTumor Pyruvate Kinase-m2BiochemistryMedicineNatural Sciences +7

Familial amyotrophic lateral sclerosis with frontotemporal dementia is linked to a locus on chromosome 9p13.2–21.3

Caroline Vance, Ammar Al‐Chalabi, Deborah Ruddy, +10

Brain

Neurological DisorderGeneticsGenetic EpidemiologyMolecular BiologyDisease Gene Identification +21

Shikonin circumvents cancer drug resistance by induction of a necroptotic death

Weidong Han, Ling Li, Shuang Qiu, +5

Molecular Cancer Therapeutics

CCNF mutations in amyotrophic lateral sclerosis and frontotemporal dementia

Kelly L. Williams, Simon Topp, Shu Yang, +65

Nature Communications

Beyond Warburg effect – dual metabolic nature of cancer cells

Hao Wu, Chunyan Dai, Qiangrong Pan, +5

Scientific Reports

Lactate and glutamine support NADPH generation in cancer cells under glucose deprived conditions

Minfeng Ying, Duo You, Xiaobing Zhu, +3

Redox Biology

Association of BDNF with restricting anorexia nervosa and minimum body mass index: a family-based association study of eight European populations

Marta Ribasès, Mónica Gratacòs, Fernando Fernández‐Aranda, +26

European Journal of Human Genetics

ObesityBody CompositionPsychiatryEating DisordersFamily-based Association Study +8

Artificial Neural Networks Analysis of Surface-Enhanced Laser Desorption/Ionization Mass Spectra of Serum Protein Pattern Distinguishes Colorectal Cancer from Healthy Population

Yiding Chen, Shu Zheng, Jiekai Yu, +1

Clinical Cancer Research

Necrostatin-1 reverts shikonin-induced necroptosis to apoptosis

Weidong Han, Ling Li, Zhen Liu, +1

APOPTOSIS

ApoptosisPathologyCell DeathHepatotoxicityNecrosis +6