Dmitry Tyrsin

Human regulatory T cells are selectively activated by low‐dose application of the CD28 superagonist TGN1412/TAB08

Paula Tabares, Susanne Berr, Paula S. Römer et al. · European Journal of Immunology · 2013 · 95 citations · Full text

Adaptive Immune System, T-regulatory Cell, Immune Regulation +22

From TGN1412 to TAB08: the return of CD28 superagonist therapy to clinical development for the treatment of rheumatoid arthritis.

Dmitry Tyrsin, Sergey Chuvpilo, Alexey A. Matskevich et al. · PubMed · 2016 · 45 citations

T-regulatory Cell, Immunology, Cd28 Superagonist Therapy +23

Cell Contact–Dependent Priming and Fc Interaction with CD32+ Immune Cells Contribute to the TGN1412-Triggered Cytokine Response

Patrick Bartholomaeus, Linda Y. Semmler, Thomas Bukur et al. · The Journal of Immunology · 2014 · 39 citations

Cell Contact–dependent Priming, Adaptive Immune System, Immunology +24

High-density preculture of PBMCs restores defective sensitivity of circulating CD8 T cells to virus- and tumor-derived antigens

Julia Wegner, Stephan Hackenberg, Claus Jürgen Scholz et al. · Blood · 2015 · 28 citations · Full text