Seiichi Hirano

Engineered CRISPR-Cas9 nuclease with expanded targeting space

Hiroshi Nishimasu, Xi Shi, Soh Ishiguro et al. · Science · 2018 · 1.1K citations

Life Sciences, Genetics, Molecular Biology +14

Cap-specific terminal <i>N</i> ⁶ -methylation of RNA by an RNA polymerase II–associated methyltransferase

Shinichiro Akichika, Seiichi Hirano, Yuichi Shichino et al. · Science · 2018 · 371 citations

Life Sciences, Genetics, Molecular Biology +14

Real-space and real-time dynamics of CRISPR-Cas9 visualized by high-speed atomic force microscopy

Mikihiro Shibata, Hiroshi Nishimasu, Noriyuki Kodera et al. · Nature Communications · 2017 · 233 citations · Full text

Life Sciences, Biology, Molecular Biology +16

Structural insights into cGAMP degradation by Ecto-nucleotide pyrophosphatase phosphodiesterase 1

Kazuki Kato, Hiroshi Nishimasu, Daisuke Oikawa et al. · Nature Communications · 2018 · 173 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Structural Basis for the Altered PAM Specificities of Engineered CRISPR-Cas9

Seiichi Hirano, Hiroshi Nishimasu, Ryuichiro Ishitani et al. · Molecular Cell · 2016 · 157 citations · Full text

Life Sciences, Genetics, Molecular Biology +15