Obesity-dependent changes in interstitial ECM mechanics promote breast tumorigenesis

Bo Ri Seo, Priya Bhardwaj, Siyoung Choi, +15

Science Translational Medicine

MechanobiologyObesityBreast OncologyMedicinePhysiology +11

Glioblastoma Stem Cells Are Regulated by Interleukin-8 Signaling in a Tumoral Perivascular Niche

David W. Infanger, Youjin Cho, Brina S. Lopez, +5

Cancer Research

Implanted adipose progenitor cells as physicochemical regulators of breast cancer

Emily M. Chandler, Bo Ri Seo, Joseph P. Califano, +14

Proceedings of the National Academy of Sciences

Breast OncologyTissue StiffnessMetabolic RemodelingBiomedical EngineeringAdipose Progenitor Cells +18

Potential Role of Peptidylarginine Deiminase Enzymes and Protein Citrullination in Cancer Pathogenesis

Sunish Mohanan, Brian D. Cherrington, Sachi Horibata, +3

Biochemistry Research International

Dysregulation of PAD4-mediated citrullination of nuclear GSK3β activates TGF-β signaling and induces epithelial-to-mesenchymal transition in breast cancer cells

Sonja C. Stadler, C. Theresa Vincent, V D Fedorov, +11

Proceedings of the National Academy of Sciences

Identification of PADI2 as a potential breast cancer biomarker and therapeutic target

John L. McElwee, Sunish Mohanan, Obi L. Griffith, +10

BMC Cancer

Identification of Macrophage Extracellular Trap-Like Structures in Mammary Gland Adipose Tissue: A Preliminary Study

Sunish Mohanan, Sachi Horibata, John L. McElwee, +2

Frontiers in Immunology

ImmunologyCls MacrophagesPathologyPreliminary StudyInflammation +18

In vivo tibial compression decreases osteolysis and tumor formation in a human metastatic breast cancer model

Maureen E. Lynch, Daniel R. Brooks, Sunish Mohanan, +6

Journal of Bone and Mineral Research

Tissue EngineeringEngineeringBone DegradationBiomedical EngineeringOsteoporosis +16

Alteration of the PKC-mediated signaling pathway for smooth muscle contraction in obstruction-induced hypertrophy of the urinary bladder

Shaohua Chang, Joseph Hypolite, Sunish Mohanan, +3

Laboratory Investigation

UrologyMolecular PhysiologySignal TransductionMuscle FunctionVoiding Dysfunction +9

IL-2–inducible T-cell kinase modulates TH2-mediated allergic airway inflammation by suppressing IFN-γ in naive CD4+ T cells

Arun Kannan, Nisebita Sahu, Sunish Mohanan, +2

Journal of Allergy and Clinical Immunology

InflammationCytokineAllergyInflammatory Lung DiseaseLung Inflammation +12