Soichiro Okubo

Gene targeting in mice reveals a requirement for angiotensin in the development and maintenance of kidney morphology and growth factor regulation.

Fumio Niimura, Patricia A. Labosky, Junji Kakuchi et al. · Journal of Clinical Investigation · 1995 · 340 citations · Full text

Pdgf-a Mrna, Hypertension, Mice Reveals +19

Murine double nullizygotes of the angiotensin type 1A and 1B receptor genes duplicate severe abnormal phenotypes of angiotensinogen nullizygotes.

S. Tsuchida, Taiji Matsusaka, X Chen et al. · Journal of Clinical Investigation · 1998 · 335 citations · Full text

Receptor Genes, Type 1, Developmental Biology +14

Targeting deletion of angiotensin type 1B receptor gene in the mouse

Xiaochun Chen, W. Li, H. Yoshida et al. · American Journal of Physiology-Renal Physiology · 1997 · 175 citations

Immunology, Reporter Gene, Receptor Gene +22

Angiotensin-independent mechanism for aldosterone synthesis during chronic extracellular fluid volume depletion.

Soichiro Okubo, Fumio Niimura, Hideki Nishimura et al. · Journal of Clinical Investigation · 1997 · 156 citations · Full text

Hypertension, Plasma Aldosterone Levels, Angiotensin-independent Mechanism +21

Angiotensinogen gene null-mutant mice lack homeostatic regulation of glomerular filtration and tubular reabsorption

Soichiro Okubo, Fumio Niimura, Taiji Matsusaka et al. · Kidney International · 1998 · 85 citations · Full text

Glomerulonephritis, Homeostatic Regulation, Urology +10