A Gαi–GIV Molecular Complex Binds Epidermal Growth Factor Receptor and Determines Whether Cells Migrate or Proliferate

Pradipta Ghosh, Anthony O. Beas, Scott J. Bornheimer, +8

Molecular Biology of the Cell

Developmental BiologySignal TransductionGef FunctionSignaling PathwayIntact Gef Motif +11

Zebrafish High‐Throughput Screening to Study the Impact of Dissolvable Metal Oxide Nanoparticles on the Hatching Enzyme, ZHE1

Sijie Lin, Yan Zhao, Zhaoxia Ji, +15

Small

NanomedicineOxide NanoparticlesEngineeringAutomated Image AnalysisBiochemistry +11

A GDI (AGS3) and a GEF (GIV) regulate autophagy by balancing G protein activity and growth factor signals

Mikel Garcia‐Marcos, Jason Ear, Marilyn G. Farquhar, +1

Molecular Biology of the Cell

MitophagyMolecular BiologyG Protein EnzymologyCellular PhysiologyRegulate Autophagy +20

Tyrosine Phosphorylation of the Gα-Interacting Protein GIV Promotes Activation of Phosphoinositide 3-Kinase During Cell Migration

Chang‐Shen Lin, Jason Ear, Yelena Pavlova, +6

Science Signaling

A Structural Determinant That Renders Gαi Sensitive to Activation by GIV/Girdin Is Required to Promote Cell Migration

Mikel Garcia‐Marcos, Pradipta Ghosh, Jason Ear, +1

Journal of Biological Chemistry

Renders Gαi SensitiveGlycobiologyHeterotrimeric G ProteinsMolecular BiologyCellular Physiology +18

E-cigarettes compromise the gut barrier and trigger inflammation

Aditi Sharma, Jasper Lee, Ayden G. Fonseca, +10

iScience

GIV is a Non‐Receptor GEF for Gαi with a Unique Motif that Regulates Akt Signaling

Mikel Garcia‐Marcos, Pradipta Ghosh, Jason Ear, +1

The FASEB Journal

Molecular RegulationImmunologyHeterotrimeric G ProteinsCancer BiologyCellular Physiology +16

Expression of GIV/Girdin, a metastasis‐related protein, predicts patient survival in colon cancer

Mikel Garcia‐Marcos, Barbara Jung, Jason Ear, +3

The FASEB Journal

Tumor BiologyInvasive ColonColorectal CancersGastrointestinal OncologyMedicine +13

Structural basis for activation of trimeric Gi proteins by multiple growth factor receptors via GIV/Girdin

Chang‐Shen Lin, Jason Ear, Krishna Midde, +6

Molecular Biology of the Cell

Defects of protein production in erythroid cells revealed in a zebrafish Diamond–Blackfan anemia model for mutation in RPS19

Yuanyuan Zhang, Jason Ear, Zhenbiao Yang, +3

Cell Death and Disease

Chromosome DynamicsDevelopmental BiologyErythroid CellsDiamond-blackfan AnemiaHeme Homeostasis +13