Design, Synthesis, and Structure–Activity Relationship Studies of Novel Fused Heterocycles-Linked Triazoles with Good Activity and Water Solubility

Xufeng Cao, Zhaoshuan Sun, Yongbing Cao, +5

Journal of Medicinal Chemistry

Bioorganic ChemistryOrganic ChemistryHeterocycles-linked TriazolesChemistryHeterocycle Chemistry +17

Selective Elevation of Adiponectin Production by the Natural Compounds Derived from a Medicinal Herb Alleviates Insulin Resistance and Glucose Intolerance in Obese Mice

Aimin Xu, Hongbing Wang, Ruby L.C. Hoo, +7

Endocrinology

Secondary MetaboliteAstragaloside IiNatural CompoundsInsulin SignalingObesity +17

Design, Synthesis, and Structure–Activity Relationship Studies of Novel Thioether Pleuromutilin Derivatives as Potent Antibacterial Agents

Chenyu Ling, Liqiang Fu, Suo Gao, +5

Journal of Medicinal Chemistry

Protopine inhibits serotonin transporter and noradrenaline transporter and has the antidepressant-like effect in mice models

Linfeng Xu, Wen‐Jing Chu, Xiao Yun-qing, +5

Neuropharmacology

PsychiatryMedicinePsychotropic MedicationNeurotransmitterNoradrenaline Transporter +10

Functional activation of monoamine transporters by luteolin and apigenin isolated from the fruit of Perilla frutescens (L.) Britt

Gang Zhao, Guo‐Wei Qin, Jie Wang, +2

Neurochemistry International

Monoamine TransportersBiochemistryMedicineExperimental PharmacologyFunctional Activation +4

Diterpenoids from the roots of<i>Euphorbia fischeriana</i>

Hongbing Wang, Wen‐Jing Chu, Ying Wang, +4

Journal of Asian Natural Products Research

Design, Synthesis, and Structure–Activity and Structure–Pharmacokinetic Relationship Studies of Novel [6,6,5] Tricyclic Fused Oxazolidinones Leading to the Discovery of a Potent, Selective, and Orally Bioavailable FXa Inhibitor

Tao Xue, Shi Ding, Bin Guo, +8

Journal of Medicinal Chemistry

Solubility-Driven Optimization of (Pyridin-3-yl) Benzoxazinyl-oxazolidinones Leading to a Promising Antibacterial Agent

Bin Guo, Houxing Fan, Qisheng Xin, +5

Journal of Medicinal Chemistry

Solubility-driven OptimizationBioorganic ChemistryPromising Antibacterial AgentAntibacterial ActivityAntimicrobial Chemotherapy +17

Monoterpene Glucosides from <i>Paeonia lactiflora</i>

Hongbing Wang, Weifeng Gu, Wen‐Jing Chu, +3

Journal of Natural Products

BiosynthesisMonoterpene GlucosidesBiochemistryPaeonia LactifloraModerate Cell-protective Activity +6

A novel compound N1,N5-(Z)-N10-(E)-tri-p-coumaroylspermidine isolated from Carthamus tinctorius L. and acting by serotonin transporter inhibition

Gang Zhao, Yue Gai, Wen‐Jing Chu, +2

European Neuropsychopharmacology

Medicinal ChemistryNovel Compound N1Serotonin Transporter InhibitionPharmaceutical ScienceBiochemistry +7