Yutaka Nishino

A Novel 1.BETA.-Methylcarbapenem Antibiotic, S-4661.Synthesis and Structure-activity Relationships of 2-(5-Substituted Pyrrolidin-3-ylthio)-1.BETA.-methylcarbapenems.

Yasuyoshi Iso, Tadashi Irie, Yutaka Nishino et al. · The Journal of Antibiotics · 1996 · 75 citations · Full text

Practical Large-Scale Synthesis of the 2-Aminomethylpyrrolidin-4-ylthio-Containing Side Chain of the Novel Carbapenem Antibiotic Doripenem

Yutaka Nishino, Tadafumi Komurasaki, Tetsuya Yuasa et al. · Organic Process Research & Development · 2003 · 22 citations

Medicinal Chemistry, Diversity Oriented Synthesis, Biochemistry +15

Practical and Scalable Synthetic Method for Preparation of Dolutegravir Sodium: Improvement of a Synthetic Route for Large-Scale Synthesis

Yasunori Aoyama, Toshikazu Hakogi, Yuki Fukui et al. · Organic Process Research & Development · 2019 · 21 citations

Experimental Synthesis, Chemical Engineering, Engineering +12

Practical Large-Scale Synthesis of Doripenem:  A Novel 1β-Methylcarbapenem Antibiotic

Yutaka Nishino, Makoto Kobayashi, Taneyoshi Shinno et al. · Organic Process Research & Development · 2003 · 15 citations

Medicinal Chemistry, Pharmaceutical Science, Natural Product Synthesis +13