Ferrostatins Inhibit Oxidative Lipid Damage and Cell Death in Diverse Disease Models

Rachid Skouta, Scott J. Dixon, Jianlin Wang, +7

Journal of the American Chemical Society

OxysterolBiochemistryMedicineLipid PeroxidationApoptosis +12

MDM2 and MDMX promote ferroptosis by PPARα-mediated lipid remodeling

Divya Venkatesh, Nicholas A. O'Brien, Fereshteh Zandkarimi, +14

Genes & Development

B7-H3-redirected chimeric antigen receptor T cells target glioblastoma and neurospheres

Dean Nehama, Natalia Di Ianni, Silvia Musio, +14

EBioMedicine

Intrabodies Binding the Proline-Rich Domains of Mutant Huntingtin Increase Its Turnover and Reduce Neurotoxicity

Amber L. Southwell, Ali Khoshnan, Denise Dunn, +3

Journal of Neuroscience

Small molecule-induced oxidation of protein disulfide isomerase is neuroprotective

Anna Kaplan, Michael M. Gaschler, Denise Dunn, +5

Proceedings of the National Academy of Sciences

Molecular BiologyChemical BiologyRedox BiologyProtein Disulfide IsomeraseOxidative Stress +16

<i>In vitro</i> and <i>in vivo</i> neuroprotective activity of the cardiac glycoside oleandrin from <i>Nerium oleander</i> in brain slice‐based stroke models

Denise Dunn, He Dong, Peiying Yang, +3

Journal of Neurochemistry

BDNF Mediates Neuroprotection against Oxygen-Glucose Deprivation by the Cardiac Glycoside Oleandrin

Michael J. Van Kanegan, He Dong, Denise Dunn, +4

Journal of Neuroscience

Bdnf Mediates NeuroprotectionLipid PeroxidationNerium OleanderCell DeathNeurochemical Biomarkers +19

IKK/NF-κB signaling contributes to glioblastoma stem cell maintenance

Amanda L. Rinkenbaugh, Patricia C. Cogswell, Barbara Calamini, +5

Oncotarget

Neuro-oncologySignaling PathwayCell RegulationGliomaGbm Expansion +12

Identification of anti-inflammatory targets for Huntington's disease using a brain slice-based screening assay

Peter H. Reinhart, Linda S. Kaltenbach, Christian Essrich, +8

Neurobiology of Disease

Alzheimer's DiseaseMedicineNeurochemical BiomarkersBrain-immune InteractionNeuroprotection +8

CalDAG-GEFI down-regulation in the striatum as a neuroprotective change in Huntington's disease

Jill R. Crittenden, Denise Dunn, Farhan I. Merali, +8

Human Molecular Genetics

Neuroprotective ChangeNeurodegenerative DiseasesSystems BiologySignal TransductionHuntingtin Protein +11