PCNA-dependent regulation of p21 ubiquitylation and degradation via the CRL4^Cdt2 ubiquitin ligase complex

Tarek Abbas, Uma Sivaprasad, Kenta Terai, +3

Genes & Development

CRL4Cdt2 Regulates Cell Proliferation and Histone Gene Expression by Targeting PR-Set7/Set8 for Degradation

Tarek Abbas, Etsuko Shibata, Jong-Hoon Park, +3

Molecular Cell

ChromatinCell RegulationChromatin RemodelingMedicineNatural Sciences +8

Ubiquitin Modification by the E3 Ligase/ADP-Ribosyltransferase Dtx3L/Parp9

Chunsong Yang, Kasey Jividen, Adam Spencer, +12

Molecular Cell

Natural SciencesProtein BiosynthesisMolecular BiologyGene ExpressionProtein Synthesis +1

CRL4Cdt2 E3 Ubiquitin Ligase Monoubiquitinates PCNA to Promote Translesion DNA Synthesis

Kenta Terai, Tarek Abbas, Amir A. Jazaeri, +1

Molecular Cell

ChromatinNucleic Acid ChemistryNatural SciencesGeneticsMolecular Biology +5

The MCM8-MCM9 Complex Promotes RAD51 Recruitment at DNA Damage Sites To Facilitate Homologous Recombination

Jong-Hoon Park, David T. Long, Kyung Yong Lee, +8

Molecular and Cellular Biology

Dna DamageGeneticsMolecular BiologyMolecular GeneticsEpigenetics +15

Differential efficacy of 3-hydroxy-3-methylglutaryl CoA reductase inhibitors on the cell cycle of prostate cancer cells

Umasundari Sivaprasad, Tarek Abbas, Anindya Dutta

Molecular Cancer Therapeutics

Combined CDK4/6 and mTOR Inhibition Is Synergistic against Glioblastoma via Multiple Mechanisms

Inan Olmez, Breanna Brenneman, Aizhen Xiao, +12

Clinical Cancer Research

MicroDNA levels are dependent on MMEJ, repressed by c-NHEJ pathway, and stimulated by DNA damage

Teressa Paulsen, Pumoli Malapati, Yoshiyuki Shibata, +5

Nucleic Acids Research

CRL1-FBXO11 Promotes Cdt2 Ubiquitylation and Degradation and Regulates Pr-Set7/Set8-Mediated Cellular Migration

Tarek Abbas, Adam C. Mueller, Etsuko Shibata, +3

Molecular Cell

Signal TransductionSignaling PathwayCell RegulationMolecular RegulationAutophagy +7

The SKP1-Cul1-F-box and Leucine-rich Repeat Protein 4 (SCF-FbxL4) Ubiquitin Ligase Regulates Lysine Demethylase 4A (KDM4A)/Jumonji Domain-containing 2A (JMJD2A) Protein

Capucine Van Rechem, Joshua C. Black, Tarek Abbas, +5

Journal of Biological Chemistry

ProteasomeMolecular BiologyCell CycleProtein ExpressionCell Regulation +17