Jiřı́ Novotný

Protein engineering of antibody binding sites: recovery of specific activity in an anti-digoxin single-chain Fv analogue produced in Escherichia coli.

James S. Huston, Dennis J. Levinson, M Mudgett-Hunter et al. · Proceedings of the National Academy of Sciences · 1988 · 1.6K citations · Full text

Engineering, Biochemistry, Molecular Biology +17

Antigenic determinants in proteins coincide with surface regions accessible to large probes (antibody domains).

Jiřı́ Novotný, Mark D. Handschumacher, E Haber et al. · Proceedings of the National Academy of Sciences · 1986 · 307 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

The C1q receptor site on immunoglobulin G

Dennis R. Burton, James G. Boyd, A. D. Brampton et al. · Nature · 1980 · 160 citations

Life Sciences, Immunology, Molecular Biology +10

Cardiac toxicity of bone marrow transplantation: predictive value of cardiologic evaluation before transplant.

Bernd Hertenstein, Martin Štefanič, T Schmeiser et al. · Journal of Clinical Oncology · 1994 · 154 citations

Medicine, Cardiology, Nuclear Medicine +17

Secondary, tertiary, and quaternary structure of T-cell-specific immunoglobulin-like polypeptide chains.

Jiřı́ Novotný, Susumu Tonegawa, Hirohisa Saito et al. · Proceedings of the National Academy of Sciences · 1986 · 144 citations · Full text

Life Sciences, Immunology, Molecular Biology +17