Basophils contribute to TH2-IgE responses in vivo via IL-4 production and presentation of peptide–MHC class II complexes to CD4+ T cells

Tomohiro Yoshimoto, Koubun Yasuda, Hidehisa Tanaka, +4

Nature Immunology

InflammationTh2-ige ResponsesAdaptive Immune SystemImmunologyImmune Regulation +10

Skin-specific expression of IL-33 activates group 2 innate lymphoid cells and elicits atopic dermatitis-like inflammation in mice

Yasutomo Imai, Koubun Yasuda, Yoshiko Sakaguchi, +5

Proceedings of the National Academy of Sciences

Japanese guidelines for the management and treatment of generalized pustular psoriasis: The new pathogenesis and treatment of <scp>GPP</scp>

Hideki Fujita, Tadashi Terui, Koremasa Hayama, +15

The Journal of Dermatology

Therapeutic depletion of myeloid lineage leukocytes in patients with generalized pustular psoriasis indicates a major role for neutrophils in the immunopathogenesis of psoriasis

Shigaku Ikeda, Hidetoshi Takahashi, Yasushi Suga, +9

Journal of the American Academy of Dermatology

InflammationGeneralized Pustular PsoriasisGranulocyteMedicineImmunology +8

Contribution of IL-18 to atopic-dermatitis-like skin inflammation induced by <i>Staphylococcus aureus</i> product in mice

Makoto Terada, Hiroko Tsutsui, Yasutomo Imai, +7

Proceedings of the National Academy of Sciences

InflammationSuper Th1 CellsAtopic DermatitisCutaneous BiologyImmunology +9

Immune-checkpoint protein VISTA critically regulates the IL-23/IL-17 inflammatory axis

Na Li, Wenwen Xu, Ying Yuan, +11

Scientific Reports

IL-33 down-regulates CLDN1 expression through the ERK/STAT3 pathway in keratinocytes

Woo‐In Ryu, Hana Lee, Hyun Cheol Bae, +10

Journal of Dermatological Science

InflammationErk/stat3 PathwayCytokineCell RegulationImmunology +7

IL-33–Induced Atopic Dermatitis–Like Inflammation in Mice Is Mediated by Group 2 Innate Lymphoid Cells in Concert with Basophils

Yasutomo Imai, Koubun Yasuda, Makoto Nagai, +4

Journal of Investigative Dermatology

Innate Lymphoid CellsImmune RegulationImmunologySkin AllergyInnate Immunity +14

Cutting Edge: PD-1 Regulates Imiquimod-Induced Psoriasiform Dermatitis through Inhibition of IL-17A Expression by Innate γδ-Low T Cells

Yasutomo Imai, Natarajan Ayithan, Xuesong Wu, +3

The Journal of Immunology

ImmunologyImmune RegulationImmunologic MechanismImmunotherapeuticsInnate Immunity +22

Protein engineering of the chemokine CCL20 prevents psoriasiform dermatitis in an IL-23–dependent murine model

Anthony E. Getschman, Yasutomo Imai, Olav Larsen, +5

Proceedings of the National Academy of Sciences

Ccl20 VariantsChemokine Ccl20ImmunologyImmune RegulationImmunologic Mechanism +26